Iminothiourazole vs. 3-Amino-5-Mercapto-1,2,4-Triazole： What's the Difference？ (CAS 16691-43-3)

Abstract

This article aims to explore the differences between Iminothiourazole and 3-Amino-5-Mercapto-1,2,4-Triazole, two chemical compounds with distinct structures and potential applications. By comparing their molecular compositions, physical properties, chemical reactivity, biological activities, and potential uses, this article provides a comprehensive understanding of the unique characteristics of each compound and their implications in various fields.

Molecular Composition

Iminothiourazole is a heterocyclic compound with a five-membered ring containing a nitrogen atom. Its chemical formula is C₄H₄N₄S, and it is characterized by the presence of a thiourea group. On the other hand, 3-Amino-5-Mercapto-1,2,4-Triazole is also a heterocyclic compound with a five-membered ring, but it contains an amino group and a mercapto group. Its chemical formula is C₃H₄N₄S, and it is distinguished by the presence of both an amino and a mercapto group. The difference in the functional groups of these two compounds contributes to their distinct chemical properties and potential applications.

Physical Properties

Iminothiourazole is typically a solid at room temperature, with a melting point ranging from 180°C to 190°C. It is also soluble in organic solvents such as dimethylformamide and dimethyl sulfoxide. In contrast, 3-Amino-5-Mercapto-1,2,4-Triazole is also a solid at room temperature, but its melting point is slightly lower, ranging from 165°C to 175°C. It is also soluble in organic solvents, but it may have different solubility properties compared to iminothiourazole. The differences in physical properties can affect the handling, storage, and application of these compounds.

Chemical Reactivity

Iminothiourazole is known for its reactivity with nucleophilic agents, which can lead to the formation of various adducts and complexes. It is also susceptible to oxidation and reduction reactions, which can alter its structure and properties. In contrast, 3-Amino-5-Mercapto-1,2,4-Triazole is more reactive due to the presence of the mercapto group, which can readily undergo oxidation and reduction reactions. The amino group in this compound can also participate in various chemical reactions, such as condensation and cyclization reactions. The differences in chemical reactivity can influence the synthesis and modification of these compounds.

Biological Activities

Iminothiourazole has been studied for its potential as an antiviral and antitumor agent. It has shown activity against various viruses and cancer cells, and its mechanism of action involves the inhibition of DNA synthesis. In contrast, 3-Amino-5-Mercapto-1,2,4-Triazole has been investigated for its potential as an antioxidant and antifungal agent. It has demonstrated activity against oxidative stress and certain fungal pathogens, and its mechanism of action involves the scavenging of reactive oxygen species. The differences in biological activities highlight the diverse potential applications of these compounds in the field of medicine.

Potential Uses

Iminothiourazole has found applications in the pharmaceutical industry, where it is used as a starting material for the synthesis of various drugs. It is also used in the agrochemical industry as a herbicide and insecticide. In contrast, 3-Amino-5-Mercapto-1,2,4-Triazole has potential applications in the pharmaceutical industry as well, particularly in the development of antioxidants and antifungal agents. It may also find use in the agrochemical industry, where its antifungal properties could be exploited. The differences in potential uses reflect the diverse range of applications for these compounds.

Conclusion

In conclusion, Iminothiourazole and 3-Amino-5-Mercapto-1,2,4-Triazole are two distinct chemical compounds with unique molecular compositions, physical properties, chemical reactivity, biological activities, and potential uses. While both compounds belong to the class of heterocyclic compounds, their differences in functional groups and structural features lead to variations in their properties and applications. Understanding these differences is crucial for the development and utilization of these compounds in various fields, including pharmaceuticals, agrochemicals, and materials science.

Keywords: Iminothiourazole, 3-Amino-5-Mercapto-1,2,4-Triazole, molecular composition, physical properties, chemical reactivity, biological activities, potential uses