The Must-Know Facts About 2-(4-Chlorobenzoyl)benzoic Acid CAS 85-56-3 for Researchers

Abstract

This article provides an in-depth overview of the essential facts about 2-(4-Chlorobenzoyl)benzoic Acid, also known as CAS 85-56-3, which is a crucial compound for researchers in various scientific fields. The article delves into the chemical properties, synthesis methods, applications, safety considerations, and environmental impact of this compound, offering valuable insights for those working with it in laboratories.

Introduction to 2-(4-Chlorobenzoyl)benzoic Acid

2-(4-Chlorobenzoyl)benzoic Acid, with the chemical formula C14H9ClO4, is a derivative of benzoic acid, characterized by the substitution of a hydrogen atom in the para position of the benzene ring with a chlorobenzoyl group. This compound is widely used in organic synthesis and has various applications in the pharmaceutical, agrochemical, and polymer industries. Understanding its properties and handling procedures is vital for researchers to ensure safe and effective experimentation.

Chemical Properties

2-(4-Chlorobenzoyl)benzoic Acid is a white crystalline solid that is soluble in organic solvents such as ethanol, acetone, and chloroform. It has a melting point of approximately 224-226°C and a boiling point of around 440°C. The compound is slightly acidic and can react with bases to form salts. Its molecular structure and functional groups make it a versatile intermediate in organic synthesis.

Synthesis Methods

The synthesis of 2-(4-Chlorobenzoyl)benzoic Acid can be achieved through various methods, including the reaction of chlorobenzoyl chloride with benzoic acid, or the condensation of chlorobenzoyl chloride with phenol in the presence of a catalyst. These methods require careful control of reaction conditions to ensure the desired product is obtained with high purity.

Applications

2-(4-Chlorobenzoyl)benzoic Acid finds extensive use in the synthesis of pharmaceuticals, agrochemicals, and polymers. It is a key intermediate in the production of certain antibiotics, antifungal agents, and herbicides. Additionally, its use in polymer chemistry is notable, as it can be employed in the synthesis of polyesters and polyamides.

Safety Considerations

Handling 2-(4-Chlorobenzoyl)benzoic Acid requires adherence to strict safety protocols. The compound is toxic if ingested, inhaled, or absorbed through the skin. Researchers should wear appropriate personal protective equipment, such as gloves, goggles, and lab coats, when working with this compound. Proper ventilation and the use of fume hoods are also essential to prevent exposure to harmful vapors.

Environmental Impact

The environmental impact of 2-(4-Chlorobenzoyl)benzoic Acid is a concern due to its potential to bioaccumulate in aquatic organisms. Its disposal should be handled with care, following local regulations and guidelines. Researchers are encouraged to explore alternative compounds with lower environmental impact when possible.

Conclusion

In conclusion, 2-(4-Chlorobenzoyl)benzoic Acid, CAS 85-56-3, is a significant compound in the field of organic chemistry, with a wide range of applications in pharmaceuticals, agrochemicals, and polymers. Understanding its chemical properties, synthesis methods, applications, safety considerations, and environmental impact is crucial for researchers to work with this compound effectively and responsibly. As the demand for this compound continues to grow, it is essential for the scientific community to stay informed about its use and potential alternatives.

Keywords

2-(4-Chlorobenzoyl)benzoic Acid, CAS 85-56-3, chemical properties, synthesis methods, applications, safety considerations, environmental impact, organic synthesis, pharmaceuticals, agrochemicals, polymers.