Veratraldehyde CAS 120-14-9： A Deep Dive into Its Chemical Properties and Applications

Abstract

This article provides a comprehensive overview of Veratraldehyde, CAS 120-14-9, delving into its chemical properties and applications. It explores the molecular structure, physical and chemical characteristics, synthesis methods, and various uses in industries such as pharmaceuticals, flavors, and fragrances. The article aims to offer a detailed understanding of Veratraldehyde's role in modern chemistry and its significance in different sectors.

Introduction to Veratraldehyde

Veratraldehyde, with the chemical formula C7H6O, is a colorless liquid with a characteristic aromatic odor. It is classified as a benzaldehyde derivative and is widely used in various industries due to its unique chemical properties. This compound is also known by several other names, including 4-hydroxybenzaldehyde and 4-hydroxybenzenealdehyde.

Chemical Properties of Veratraldehyde

Veratraldehyde possesses several distinct chemical properties that make it valuable in various applications. Firstly, it is a volatile compound, which allows it to be easily evaporated and used in different processes. Secondly, it is a strong reducing agent, which enables it to participate in various redox reactions. Lastly, it is a reactive compound that can undergo various chemical transformations, such as condensation, polymerization, and substitution reactions.

Physical Characteristics of Veratraldehyde

Veratraldehyde has a melting point of approximately 16.5°C and a boiling point of around 257°C. It is soluble in water, alcohol, and ether, which makes it easy to handle and use in different applications. However, it is important to note that Veratraldehyde is highly flammable and should be handled with care to avoid accidents.

Synthesis of Veratraldehyde

Veratraldehyde can be synthesized through various methods, including the oxidation of benzaldehyde, the reaction of hydroquinone with formaldehyde, and the hydrolysis of 4-hydroxybenzoic acid. The most common method involves the oxidation of benzaldehyde using sodium hypochlorite or potassium permanganate. This process is cost-effective and produces high yields of Veratraldehyde.

Applications of Veratraldehyde

Veratraldehyde finds extensive use in various industries due to its unique properties. In the pharmaceutical industry, it is used as a raw material for the synthesis of antifungal agents, analgesics, and cardiovascular drugs. In the flavors and fragrances industry, it is used to create a wide range of natural and synthetic flavors and fragrances, such as almond, cherry, and vanilla.

Environmental and Health Concerns

Despite its numerous applications, Veratraldehyde is not without its environmental and health concerns. It is classified as a hazardous substance due to its potential to cause irritation to the skin, eyes, and respiratory system. Long-term exposure to Veratraldehyde may lead to serious health issues, including cancer. Therefore, it is crucial to handle this compound with appropriate safety measures and regulations.

Conclusion

In conclusion, Veratraldehyde, CAS 120-14-9, is a versatile compound with a wide range of applications in various industries. Its unique chemical properties, such as volatility, reactivity, and solubility, make it an essential component in the synthesis of pharmaceuticals, flavors, and fragrances. However, it is important to be aware of the environmental and health risks associated with Veratraldehyde and to handle it with appropriate safety measures.

Keywords: Veratraldehyde, CAS 120-14-9, chemical properties, applications, synthesis, pharmaceuticals, flavors, fragrances, environmental concerns, health risks.