Benzohydroxamic Acid CAS 495-18-1: Everything You Need to Know About This Molecule

January 16, 2025

Abstract

This article provides an in-depth overview of Benzohydroxamic Acid (CAS 495-18-1), a molecule with significant implications in various scientific fields. It explores the chemical structure, properties, synthesis methods, applications, and safety considerations associated with this compound. By delving into these aspects, the article aims to offer a comprehensive understanding of Benzohydroxamic Acid, its uses, and its importance in modern chemistry.

Introduction to Benzohydroxamic Acid (CAS 495-18-1)

Benzohydroxamic Acid, with the chemical formula C7H7NO3, is a compound that has garnered attention due to its unique chemical properties and potential applications. It is classified as a hydroxamic acid and is known for its ability to form stable complexes with metal ions. This article will explore the various facets of Benzohydroxamic Acid, including its chemical structure, synthesis, properties, and uses.

Chemical Structure and Properties

The chemical structure of Benzohydroxamic Acid consists of a benzene ring with a hydroxamic acid group attached. This structure allows for the formation of coordination complexes with metal ions, which is a key property that contributes to its applications. The hydroxamic acid group is characterized by its ability to donate a lone pair of electrons to metal ions, forming coordination bonds. This property makes Benzohydroxamic Acid a versatile ligand in various chemical reactions.

The physical properties of Benzohydroxamic Acid include a melting point of approximately 180-182°C and a boiling point of around 300°C. It is a white crystalline solid that is soluble in water and organic solvents. These properties make it suitable for various applications, including synthesis and analytical chemistry.

Synthesis of Benzohydroxamic Acid

The synthesis of Benzohydroxamic Acid can be achieved through several methods, each with its own advantages and limitations. One common method involves the reaction of benzaldehyde with hydroxylamine hydrochloride in the presence of a base, such as sodium hydroxide. This reaction leads to the formation of Benzohydroxamic Acid and water.

Another synthesis method involves the reaction of benzaldehyde with sodium nitrite in the presence of hydrochloric acid, followed by reduction with sodium borohydride. This process results in the formation of Benzohydroxamic Acid as a byproduct.

The choice of synthesis method depends on factors such as the desired purity of the compound, the scale of production, and the availability of starting materials.

Applications of Benzohydroxamic Acid

Benzohydroxamic Acid finds applications in various fields, including pharmaceuticals, agriculture, and analytical chemistry. In the pharmaceutical industry, it is used as a precursor for the synthesis of various drugs, including antiviral agents and anti-inflammatory compounds.

In agriculture, Benzohydroxamic Acid is used as a herbicide due to its ability to inhibit the growth of certain plants. It is also employed as a fungicide to control fungal infections in crops.

Analytical chemistry utilizes Benzohydroxamic Acid as a chelating agent to remove metal ions from solutions, which is crucial for the purification of samples before analysis.

Safety Considerations

As with any chemical compound, Benzohydroxamic Acid has certain safety considerations. It is important to handle the compound with care, as it can cause irritation to the skin, eyes, and respiratory system. Adequate personal protective equipment, such as gloves and safety goggles, should be worn when handling the compound.

In terms of environmental impact, Benzohydroxamic Acid is considered to be moderately toxic to aquatic organisms. Therefore, proper disposal methods should be followed to minimize its impact on the environment.

Conclusion

In conclusion, Benzohydroxamic Acid (CAS 495-18-1) is a versatile molecule with a range of applications in various scientific fields. Its unique chemical structure and properties make it a valuable compound in pharmaceuticals, agriculture, and analytical chemistry. Understanding the synthesis, properties, and safety considerations associated with Benzohydroxamic Acid is crucial for its effective use and responsible handling.

Keywords: Benzohydroxamic Acid, CAS 495-18-1, chemical structure, synthesis, properties, applications, safety considerations

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