The Ultimate Guide to CAS 127464-43-1: 2-Ethyl-6-Methyl-3-Hydroxypyridine Succinate Breakdown

January 16, 2025

Abstract

This article provides an in-depth guide to the breakdown of 2-Ethyl-6-Methyl-3-Hydroxypyridine Succinate, a chemical compound with CAS number 127464-43-1. The guide covers various aspects of the compound, including its structure, synthesis, properties, degradation pathways, environmental impact, and potential applications. By exploring these facets, the article aims to offer a comprehensive understanding of the compound and its breakdown process.

Introduction to 2-Ethyl-6-Methyl-3-Hydroxypyridine Succinate

2-Ethyl-6-Methyl-3-Hydroxypyridine Succinate, with the CAS number 127464-43-1, is a chemical compound that belongs to the pyridine family. It is characterized by a pyridine ring with an ethyl group, a methyl group, and a hydroxyl group attached to the third position. This compound has various applications in the pharmaceutical and chemical industries, and its breakdown is a critical process to ensure safety and environmental compliance.

Chemical Structure and Properties

The chemical structure of 2-Ethyl-6-Methyl-3-Hydroxypyridine Succinate consists of a pyridine ring with a hydroxyl group at the third position, an ethyl group at the second position, and a methyl group at the sixth position. The succinate group is attached to the pyridine ring, contributing to the compound's solubility and stability. The presence of the hydroxyl and succinate groups makes the compound polar, which affects its physical and chemical properties.

The physical properties of 2-Ethyl-6-Methyl-3-Hydroxypyridine Succinate include a melting point of approximately 150°C and a boiling point of around 300°C. It is soluble in water, alcohol, and other polar solvents, which makes it suitable for various applications. The compound's chemical properties are influenced by the presence of the hydroxyl and succinate groups, which can participate in various chemical reactions, such as esterification, hydrolysis, and oxidation.

Synthesis of 2-Ethyl-6-Methyl-3-Hydroxypyridine Succinate

The synthesis of 2-Ethyl-6-Methyl-3-Hydroxypyridine Succinate involves several steps, including the preparation of the pyridine ring, the introduction of the ethyl and methyl groups, and the attachment of the succinate group. The synthesis process typically starts with the formation of the pyridine ring, which can be achieved through various methods, such as the Knoevenagel condensation or the Biginelli reaction.

Once the pyridine ring is formed, the ethyl and methyl groups are introduced through nucleophilic substitution reactions. The succinate group is then attached to the pyridine ring using a coupling reaction, such as the Suzuki-Miyaura coupling or the Stille coupling. The overall synthesis process requires careful control of reaction conditions to ensure the desired product is obtained with high purity.

Breakdown Pathways

The breakdown of 2-Ethyl-6-Methyl-3-Hydroxypyridine Succinate can occur through various pathways, including hydrolysis, oxidation, and photolysis. Hydrolysis is the most common breakdown pathway, where the succinate group is cleaved, resulting in the formation of 2-Ethyl-6-Methyl-3-Hydroxypyridine and succinic acid. This process is typically facilitated by the presence of water and can occur under both acidic and alkaline conditions.

Oxidation is another significant breakdown pathway, where the hydroxyl and methyl groups are oxidized to form carboxylic acids and aldehydes. This process can be catalyzed by various oxidizing agents, such as hydrogen peroxide or potassium permanganate. Photolysis, on the other hand, involves the decomposition of the compound upon exposure to light, leading to the formation of various by-products.

Environmental Impact

The breakdown of 2-Ethyl-6-Methyl-3-Hydroxypyridine Succinate can have significant environmental implications. The formation of by-products, such as carboxylic acids and aldehydes, can contribute to water and soil pollution. Additionally, the release of volatile organic compounds (VOCs) during the breakdown process can contribute to air pollution and the formation of ground-level ozone.

To mitigate the environmental impact, it is crucial to implement proper waste management and treatment processes. This includes the separation of the compound from other waste streams, the use of biodegradable materials, and the implementation of advanced treatment technologies, such as activated carbon adsorption or biological treatment.

Potential Applications

Despite the potential environmental concerns, 2-Ethyl-6-Methyl-3-Hydroxypyridine Succinate has various applications in the pharmaceutical and chemical industries. It is used as a precursor for the synthesis of pharmaceuticals, such as antiviral and antibacterial agents. The compound can also be used as a building block for the development of new materials, including polymers and coatings.

The versatility of 2-Ethyl-6-Methyl-3-Hydroxypyridine Succinate makes it a valuable compound in research and development. However, it is essential to consider the potential environmental impact of its use and to implement appropriate safety measures to minimize risks.

Conclusion

In conclusion, this article has provided a comprehensive guide to the breakdown of 2-Ethyl-6-Methyl-3-Hydroxypyridine Succinate, a chemical compound with CAS number 127464-43-1. The guide has covered various aspects of the compound, including its chemical structure, synthesis, properties, breakdown pathways, environmental impact, and potential applications. By understanding these facets, researchers, manufacturers, and regulatory agencies can make informed decisions regarding the use and disposal of this compound, ensuring safety and environmental compliance.

Keywords: 2-Ethyl-6-Methyl-3-Hydroxypyridine Succinate, CAS 127464-43-1, breakdown pathways, environmental impact, potential applications, synthesis

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