Unlock the Secrets of 4-Chloro-4′-Hydroxybenzophenone CAS 42019-78-3: A Comprehensive Guide

January 16, 2025

Abstract

This comprehensive guide delves into the mysteries of 4-Chloro-4′-Hydroxybenzophenone, a chemical compound with the CAS number 42019-78-3. The article explores its synthesis, properties, applications, and safety considerations, providing a detailed overview for researchers, chemists, and those interested in the field of organic chemistry.

Introduction to 4-Chloro-4′-Hydroxybenzophenone

4-Chloro-4′-Hydroxybenzophenone, also known as 4-chloro-4'-hydroxybiphenyl, is a compound that belongs to the class of hydroxybenzophenones. It is characterized by the presence of a chlorine atom and a hydroxyl group attached to the benzene rings. This compound has gained significant attention due to its unique properties and potential applications in various fields.

Synthesis of 4-Chloro-4′-Hydroxybenzophenone

The synthesis of 4-Chloro-4′-Hydroxybenzophenone involves several steps, including the preparation of the starting materials and the reaction conditions required for the formation of the desired compound. One common method involves the reaction of 4-chlorobenzophenone with a hydroxylating agent, such as sodium hydroxide or potassium permanganate, under controlled conditions. The reaction yields the desired compound with high purity and efficiency.

Properties of 4-Chloro-4′-Hydroxybenzophenone

4-Chloro-4′-Hydroxybenzophenone exhibits several distinct properties that make it valuable in various applications. It has a melting point of approximately 140-142°C and a boiling point of around 300°C. The compound is soluble in organic solvents such as acetone, ethanol, and chloroform but is sparingly soluble in water. Its physical properties, such as melting point and solubility, are crucial factors to consider during its synthesis and application processes.

Applications of 4-Chloro-4′-Hydroxybenzophenone

The versatility of 4-Chloro-4′-Hydroxybenzophenone makes it suitable for a wide range of applications. It is used as a precursor in the synthesis of pharmaceuticals, agrochemicals, and dyes. The compound's ability to undergo various chemical transformations allows for the development of new compounds with desired properties. Additionally, its use in organic synthesis has expanded its applications in materials science and polymer chemistry.

Safety Considerations

As with any chemical compound, safety considerations are paramount when handling 4-Chloro-4′-Hydroxybenzophenone. The compound is considered hazardous due to its potential to cause skin irritation, respiratory irritation, and allergic reactions. Proper handling, storage, and disposal procedures are essential to minimize the risks associated with its use. Personal protective equipment, such as gloves, goggles, and lab coats, should be worn when working with this compound.

Regulatory Compliance

Compliance with regulatory standards is crucial for the safe and legal use of 4-Chloro-4′-Hydroxybenzophenone. The compound falls under various regulations, including the European Union's REACH (Registration, Evaluation, Authorisation, and Restriction of Chemicals) and the United States' Toxic Substances Control Act (TSCA). Adhering to these regulations ensures that the compound is used responsibly and in accordance with environmental and health standards.

Conclusion

In conclusion, 4-Chloro-4′-Hydroxybenzophenone CAS 42019-78-3 is a versatile compound with significant potential in various fields. This comprehensive guide has provided an in-depth analysis of its synthesis, properties, applications, and safety considerations. Understanding these aspects is crucial for researchers, chemists, and those involved in the production and use of this compound. As the demand for advanced materials and pharmaceuticals continues to grow, the knowledge gained from this guide will undoubtedly contribute to the development of innovative solutions.

Keywords: 4-Chloro-4′-Hydroxybenzophenone, CAS 42019-78-3, synthesis, properties, applications, safety considerations, regulatory compliance

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