4-Chloro-4′-Hydroxybenzophenone CAS 42019-78-3: The Key to Unraveling Its Chemical Properties

January 16, 2025

Abstract

This article provides a comprehensive overview of the chemical properties of 4-Chloro-4′-Hydroxybenzophenone CAS 42019-78-3, a compound that has garnered significant interest in the field of organic chemistry. The article delves into the synthesis, structural analysis, reactivity, biological significance, and potential applications of this compound, offering insights into its unique characteristics and its role in various chemical reactions and processes.

Introduction to 4-Chloro-4′-Hydroxybenzophenone CAS 42019-78-3

4-Chloro-4′-Hydroxybenzophenone, with the CAS number 42019-78-3, is a benzophenone derivative characterized by the presence of a chlorine atom and a hydroxyl group at the 4 and 4′ positions, respectively. This compound has been the subject of extensive research due to its intriguing chemical properties and potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science.

Synthesis of 4-Chloro-4′-Hydroxybenzophenone

The synthesis of 4-Chloro-4′-Hydroxybenzophenone involves several steps, including the preparation of the starting materials and the subsequent reactions to introduce the chlorine and hydroxyl groups. One common method involves the reaction of 4-chlorobenzophenone with a hydroxylating agent, such as sodium hydroxide or hydrogen peroxide, under appropriate reaction conditions. The resulting compound is then purified through recrystallization or chromatography to obtain the desired purity.

Structural Analysis of 4-Chloro-4′-Hydroxybenzophenone

The structural analysis of 4-Chloro-4′-Hydroxybenzophenone is crucial for understanding its chemical properties. Techniques such as nuclear magnetic resonance (NMR) spectroscopy, infrared (IR) spectroscopy, and mass spectrometry (MS) are employed to determine the molecular structure and the functional groups present. These analyses reveal that the compound has a planar structure with the chlorine and hydroxyl groups in close proximity, which can influence its reactivity.

Reactivity of 4-Chloro-4′-Hydroxybenzophenone

The reactivity of 4-Chloro-4′-Hydroxybenzophenone is a key aspect of its chemical properties. The presence of the hydroxyl group makes the compound susceptible to nucleophilic substitution reactions, while the chlorine atom can participate in electrophilic aromatic substitution reactions. Additionally, the compound can undergo oxidation and reduction reactions, which can be exploited in various synthetic transformations.

Biological Significance of 4-Chloro-4′-Hydroxybenzophenone

4-Chloro-4′-Hydroxybenzophenone has shown potential biological significance, particularly in the context of drug discovery. The compound has been found to exhibit antifungal, antibacterial, and antiviral properties, making it a promising candidate for the development of new therapeutic agents. Its unique structural features may contribute to its biological activity, and further research is ongoing to elucidate the exact mechanisms of action.

Potential Applications of 4-Chloro-4′-Hydroxybenzophenone

The potential applications of 4-Chloro-4′-Hydroxybenzophenone are diverse and include its use as a building block in the synthesis of complex organic molecules, a precursor in the production of agrochemicals, and a component in the development of new materials. Its unique combination of functional groups makes it a versatile compound with a wide range of applications in the chemical industry.

Conclusion

In conclusion, 4-Chloro-4′-Hydroxybenzophenone CAS 42019-78-3 is a compound of significant interest due to its unique chemical properties and potential applications. Its synthesis, structural analysis, reactivity, biological significance, and potential uses have been thoroughly explored in this article. As research continues to unfold, it is likely that this compound will play an increasingly important role in various scientific and industrial fields.

Keywords: 4-Chloro-4′-Hydroxybenzophenone, CAS 42019-78-3, chemical properties, synthesis, structural analysis, reactivity, biological significance, potential applications.

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