Maleic Hydrazide Potassium Salt (CAS 28382-15-2): Everything You Need to Know About This Compound

January 16, 2025

Abstract

This article provides an in-depth overview of Maleic Hydrazide Potassium Salt (CAS 28382-15-2), a compound with significant applications in various industries. It covers its chemical properties, synthesis methods, uses, safety considerations, environmental impact, and regulatory status. By exploring these aspects, the article aims to offer a comprehensive understanding of this compound and its importance in modern chemistry.

Introduction to Maleic Hydrazide Potassium Salt (CAS 28382-15-2)

Maleic Hydrazide Potassium Salt, also known as potassium maleic hydrazide, is a chemical compound with the formula KCH(CN)2. It is a white crystalline solid that is soluble in water and slightly soluble in organic solvents. This compound is widely used in the synthesis of pharmaceuticals, agrochemicals, and other chemicals. Its unique properties make it a valuable intermediate in various chemical reactions.

Chemical Properties

Maleic Hydrazide Potassium Salt is an organic compound that belongs to the hydrazide family. It contains a maleic acid group and a hydrazine group, which gives it its characteristic chemical properties. The compound is highly reactive and can undergo various chemical transformations, such as hydrolysis, oxidation, and reduction. These properties make it a versatile reagent in organic synthesis.

Synthesis Methods

The synthesis of Maleic Hydrazide Potassium Salt can be achieved through several methods. One common approach involves the reaction of maleic anhydride with hydrazine monohydrochloride in the presence of a base, such as potassium hydroxide. This reaction yields the potassium salt as a white crystalline solid. Another method involves the reaction of maleic acid with hydrazine hydrate in the presence of a base, which also results in the formation of the potassium salt.

Uses

Maleic Hydrazide Potassium Salt finds applications in various industries. In the pharmaceutical industry, it is used as a precursor for the synthesis of antiviral drugs, such as acyclovir. In agrochemicals, it is used as a herbicide and fungicide. Additionally, it is employed in the production of dyes, plastics, and other chemicals. Its versatility makes it a valuable compound in many chemical processes.

Safety Considerations

As with any chemical compound, safety considerations are crucial when handling Maleic Hydrazide Potassium Salt. The compound is toxic if ingested, inhaled, or absorbed through the skin. It can cause irritation to the eyes, skin, and respiratory system. Therefore, appropriate personal protective equipment, such as gloves, goggles, and masks, should be worn when working with this compound. Proper ventilation and adherence to safety protocols are essential to minimize the risk of exposure.

Environmental Impact

The environmental impact of Maleic Hydrazide Potassium Salt is a subject of concern. The compound is considered moderately hazardous to aquatic life and may cause long-term adverse effects in the aquatic environment. It is also classified as a priority hazardous substance under the European Union's REACH regulation. Proper disposal methods and environmental protection measures are necessary to mitigate its impact on the environment.

Regulatory Status

The regulatory status of Maleic Hydrazide Potassium Salt varies by country and region. In the United States, it is regulated under the Toxic Substances Control Act (TSCA) and the Occupational Safety and Health Administration (OSHA) standards. In the European Union, it is subject to the Registration, Evaluation, Authorisation, and Restriction of Chemicals (REACH) regulation. Compliance with these regulations is essential for the safe use and handling of the compound.

Conclusion

In conclusion, Maleic Hydrazide Potassium Salt (CAS 28382-15-2) is a versatile compound with significant applications in various industries. Its chemical properties, synthesis methods, uses, safety considerations, environmental impact, and regulatory status are all important aspects to consider when dealing with this compound. By understanding these factors, researchers, manufacturers, and users can ensure the safe and responsible use of Maleic Hydrazide Potassium Salt.

Keywords: Maleic Hydrazide Potassium Salt, CAS 28382-15-2, chemical properties, synthesis methods, uses, safety considerations, environmental impact, regulatory status.

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