The Ultimate Guide to Understanding CAS 30165-96-9： 3-Chloro-4-Morpholino-1,2,5-Thiadiazole

Abstract

This article provides a comprehensive guide to understanding CAS 30165-96-9, which is a chemical compound known as 3-Chloro-4-morpholino-1,2,5-thiadiazole. The guide delves into the chemical structure, properties, synthesis methods, applications, safety considerations, and environmental impact of this compound. By exploring these aspects, the article aims to offer a thorough understanding of this chemical and its significance in various fields.

Introduction to CAS 30165-96-9: 3-Chloro-4-Morpholino-1,2,5-Thiadiazole

CAS 30165-96-9, also known as 3-Chloro-4-morpholino-1,2,5-thiadiazole, is a synthetic organic compound that belongs to the thiadiazole family. This compound is characterized by its unique chemical structure, which includes a thiadiazole ring with a chlorine atom and a morpholino group. The compound has various applications in the pharmaceutical, agricultural, and industrial sectors.

Chemical Structure and Properties

The chemical structure of CAS 30165-96-9 consists of a thiadiazole ring, which is a five-membered heterocyclic compound containing one sulfur atom and two nitrogen atoms. The presence of a chlorine atom and a morpholino group introduces additional functional groups to the molecule. These functional groups contribute to the compound's unique properties, such as its solubility in organic solvents and its reactivity towards various chemical reactions.

The molecular formula of CAS 30165-96-9 is C7H7ClN2S, and its molecular weight is 194.69 g/mol. The compound has a melting point of approximately 244-246°C and a boiling point of around 425°C. It is a white to off-white solid that is stable under normal conditions but may decompose upon heating.

Synthesis Methods

The synthesis of CAS 30165-96-9 involves several steps, including the reaction of 3-chloro-4-methylthiazole with morpholine in the presence of a catalyst. The reaction typically proceeds via a nucleophilic substitution mechanism, where the morpholine attacks the chlorine atom of the thiadiazole ring. The resulting intermediate is then cyclized to form the final product.

Other methods for synthesizing CAS 30165-96-9 include the reaction of 3-chloro-4-methylthiazole with morpholine in the presence of a base, such as potassium hydroxide or sodium hydroxide. This method also involves a nucleophilic substitution followed by cyclization.

Applications

CAS 30165-96-9 finds applications in various fields, including pharmaceuticals, agriculture, and industrial chemicals. In the pharmaceutical industry, the compound is used as a starting material for the synthesis of active pharmaceutical ingredients (APIs) and intermediates. It is also used as a stabilizer in pharmaceutical formulations.

In agriculture, CAS 30165-96-9 is employed as a herbicide due to its ability to inhibit the growth of weeds. It is effective against a wide range of weeds and is considered to be environmentally friendly compared to other herbicides.

In the industrial sector, the compound is used as a raw material for the production of dyes, pigments, and other specialty chemicals. Its unique properties make it suitable for applications in the synthesis of high-performance materials.

Safety Considerations

As with any chemical compound, safety considerations are crucial when handling CAS 30165-96-9. The compound is toxic if ingested, inhaled, or absorbed through the skin. It is recommended to wear appropriate personal protective equipment (PPE), such as gloves, goggles, and lab coats, when working with this compound.

In case of accidental exposure, immediate medical attention should be sought. The compound should be stored in a cool, dry place away from incompatible materials and in a tightly sealed container. Proper waste disposal procedures should be followed to minimize environmental impact.

Environmental Impact

The environmental impact of CAS 30165-96-9 is a subject of concern, especially in its use as a herbicide. The compound can be harmful to aquatic life and soil microorganisms if not used properly. Therefore, it is essential to follow recommended application rates and guidelines to minimize environmental contamination.

Research is ongoing to develop more environmentally friendly alternatives to CAS 30165-96-9. These alternatives aim to reduce the compound's toxicity to non-target organisms and its persistence in the environment.

Conclusion

In conclusion, CAS 30165-96-9, or 3-Chloro-4-morpholino-1,2,5-thiadiazole, is a versatile chemical compound with various applications in the pharmaceutical, agricultural, and industrial sectors. Understanding its chemical structure, properties, synthesis methods, applications, safety considerations, and environmental impact is crucial for its safe and effective use. As research continues to evolve, it is essential to stay informed about the latest developments in the field to ensure the responsible use of this compound.

Keywords: CAS 30165-96-9, 3-Chloro-4-morpholino-1,2,5-thiadiazole, chemical structure, properties, synthesis, applications, safety, environmental impact