Unlock the Secrets of Sodium Butazolidine CAS 129-18-0： A Comprehensive Guide

Abstract

This article provides a comprehensive guide to sodium butazolidine, a chemical compound with the CAS number 129-18-0. It delves into the various aspects of sodium butazolidine, including its chemical properties, synthesis methods, applications, safety considerations, and regulatory aspects. The guide aims to unlock the secrets of this compound, offering insights into its uses and potential risks, making it a valuable resource for researchers, pharmaceutical professionals, and anyone interested in the field of organic chemistry.

Introduction to Sodium Butazolidine

Sodium butazolidine, with the chemical formula C10H10N2NaO2, is a white crystalline solid that belongs to the class of heterocyclic compounds. It is commonly used as a pharmaceutical agent due to its anti-inflammatory, analgesic, and antipyretic properties. This guide will explore the various facets of sodium butazolidine, providing a thorough understanding of its characteristics and applications.

Chemical Properties of Sodium Butazolidine

Sodium butazolidine is a derivative of the pyrazolidine ring system, which is characterized by its five-membered ring containing two nitrogen atoms. The presence of these nitrogen atoms contributes to the compound's basicity, making it suitable for various chemical reactions. The molecular weight of sodium butazolidine is 202.18 g/mol, and it has a melting point of approximately 244-246°C. Its solubility in water is relatively low, which is a characteristic that can affect its pharmaceutical formulation.

Synthesis of Sodium Butazolidine

The synthesis of sodium butazolidine involves several steps, including the condensation of 2-aminobutane with 2-chloropyridine followed by neutralization with sodium hydroxide. This process requires careful control of reaction conditions to ensure the desired product is obtained. Alternative synthetic routes, such as the reaction of 2-aminobutane with 2-chloropyridine in the presence of a catalyst, have also been explored to improve the yield and purity of the compound.

Applications of Sodium Butazolidine

Sodium butazolidine is primarily used as a pharmaceutical agent for the treatment of inflammatory diseases, such as arthritis, and for the relief of pain and fever. It is often prescribed in the form of tablets or injections. The compound's anti-inflammatory properties make it a valuable component in the development of new medications for the management of chronic pain and inflammatory conditions.

Safety Considerations and Side Effects

While sodium butazolidine is effective in treating certain conditions, it is not without its risks. The compound can cause gastrointestinal irritation, leading to nausea, vomiting, and stomach pain. Long-term use may also increase the risk of kidney and liver damage. As a result, it is crucial for healthcare professionals to monitor patients closely when prescribing sodium butazolidine and to consider alternative treatments when appropriate.

Regulatory Aspects of Sodium Butazolidine

The use of sodium butazolidine is regulated by various authorities, including the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA). These organizations ensure that the compound is used safely and effectively by establishing guidelines for its manufacturing, labeling, and distribution. Compliance with these regulations is essential for pharmaceutical companies and healthcare providers.

Conclusion

Unlocking the secrets of sodium butazolidine, as detailed in this comprehensive guide, provides a valuable resource for understanding the compound's chemical properties, synthesis methods, applications, safety considerations, and regulatory aspects. By exploring these various facets, researchers and professionals can make informed decisions regarding the use of sodium butazolidine in pharmaceutical development and patient care.

Keywords: sodium butazolidine, CAS 129-18-0, chemical properties, synthesis, applications, safety, regulatory aspects