The Complete Guide to 2-(2-Aminothiazol-4-yl) Acetic Acid Hydrochloride CAS 66659-20-9: Benefits, Uses, and More

January 30, 2025

Abstract

This article provides a comprehensive guide to 2-(2-aminothiazol-4-yl) acetic acid hydrochloride, CAS 66659-20-9. It delves into the benefits, uses, and various aspects of this compound, offering insights into its chemical properties, synthesis methods, applications in pharmaceuticals, and safety considerations. The article aims to serve as a valuable resource for researchers, scientists, and professionals in the field of organic chemistry and pharmaceutical development.

Introduction to 2-(2-Aminothiazol-4-yl) Acetic Acid Hydrochloride

2-(2-aminothiazol-4-yl) acetic acid hydrochloride, with the CAS number 66659-20-9, is a synthetic organic compound that has gained significant attention in recent years. This compound is a derivative of acetic acid, featuring a thiazole ring substituted with an amino group. Its unique chemical structure and properties make it a valuable compound in various applications, including pharmaceuticals, agrochemicals, and materials science.

Chemical Properties

The chemical properties of 2-(2-aminothiazol-4-yl) acetic acid hydrochloride are characterized by its yellowish crystalline appearance and its solubility in water and organic solvents. The compound has a molecular weight of 265.74 g/mol and a melting point of approximately 265°C. It is also known for its stability under normal storage conditions, making it suitable for long-term storage.

Synthesis Methods

The synthesis of 2-(2-aminothiazol-4-yl) acetic acid hydrochloride can be achieved through various methods, including the condensation reaction between 2-aminothiazole and chloroacetic acid. This reaction typically involves the use of a catalyst, such as amines or alkali metals, to facilitate the formation of the desired compound. Alternative synthesis methods, such as the reaction of 2-aminothiazole with acetic anhydride, also exist and can be employed depending on the desired scale and purity of the final product.

Benefits of 2-(2-Aminothiazol-4-yl) Acetic Acid Hydrochloride

The benefits of 2-(2-aminothiazol-4-yl) acetic acid hydrochloride are multifaceted. Firstly, its unique chemical structure allows for the development of novel pharmaceuticals with potential therapeutic applications. Secondly, the compound exhibits excellent solubility properties, making it suitable for formulation into various dosage forms. Lastly, its stability and ease of synthesis contribute to its cost-effectiveness and widespread use in research and development.

Applications in Pharmaceuticals

In the pharmaceutical industry, 2-(2-aminothiazol-4-yl) acetic acid hydrochloride serves as a key intermediate in the synthesis of various drugs. Its versatile chemical properties enable the development of compounds with diverse therapeutic effects, including anti-inflammatory, analgesic, and antiviral activities. Additionally, the compound has been explored for its potential use in cancer therapy, where it may exhibit selective toxicity against tumor cells.

Use in Agrochemicals

The agrochemical industry also benefits from the use of 2-(2-aminothiazol-4-yl) acetic acid hydrochloride. This compound can be utilized as an active ingredient in herbicides, fungicides, and insecticides, offering effective solutions for crop protection. Its unique chemical structure allows for the development of compounds with improved efficacy and reduced environmental impact.

Safety Considerations

As with any chemical compound, safety considerations are paramount when dealing with 2-(2-aminothiazol-4-yl) acetic acid hydrochloride. Proper handling, storage, and disposal protocols must be followed to minimize the risk of exposure to both humans and the environment. It is essential to wear appropriate personal protective equipment and to ensure that the compound is stored in a cool, dry place away from incompatible materials.

Conclusion

In conclusion, 2-(2-aminothiazol-4-yl) acetic acid hydrochloride, CAS 66659-20-9, is a versatile and valuable compound with numerous benefits and applications. Its unique chemical properties, synthesis methods, and potential uses in pharmaceuticals and agrochemicals highlight its significance in various scientific and industrial fields. As research continues to unfold, the compound is expected to contribute further to advancements in medicine and agriculture.

Keywords: 2-(2-aminothiazol-4-yl) acetic acid hydrochloride, CAS 66659-20-9, chemical properties, synthesis methods, pharmaceutical applications, agrochemicals, safety considerations.

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