1,4-Cyclohexanediol CAS 556-48-9： Everything You Need to Know About This Chemical

Abstract

This article provides an in-depth overview of 1,4-Cyclohexanediol, a chemical with the CAS number 556-48-9. It delves into its chemical properties, synthesis methods, applications, health and safety considerations, environmental impact, and regulatory status. By exploring these aspects, the article aims to offer a comprehensive understanding of this chemical and its significance in various industries.

Introduction to 1,4-Cyclohexanediol

1,4-Cyclohexanediol, also known as 1,4-cyclohexanedione, is a colorless, crystalline solid with a molecular formula of C6H10O2. It is a diol, meaning it contains two hydroxyl (-OH) groups attached to a cyclohexane ring. This chemical is widely used in the production of various polymers, resins, and other industrial products. In this article, we will explore the various aspects of 1,4-Cyclohexanediol, including its synthesis, properties, applications, and safety considerations.

Chemical Properties of 1,4-Cyclohexanediol

1,4-Cyclohexanediol is a stable compound with a melting point of approximately 153°C and a boiling point of around 284°C. It is soluble in water, alcohols, and ethers, making it easy to handle and process in industrial settings. The compound is also known for its high reactivity, which allows it to participate in various chemical reactions, such as polymerization and condensation reactions.

The presence of the two hydroxyl groups in 1,4-Cyclohexanediol makes it a versatile intermediate in the synthesis of polyesters, polyurethanes, and other polymers. These hydroxyl groups can react with carboxylic acids or esters to form esters or polyesters, respectively. Additionally, the compound can undergo dehydration to form cyclohexanone, which is another important chemical intermediate.

Synthesis of 1,4-Cyclohexanediol

The synthesis of 1,4-Cyclohexanediol can be achieved through various methods, including the hydrolysis of cyclohexanone, the hydrogenation of cyclohexene-1,4-dicarboxylic acid, and the oxidation of cyclohexane. The most common industrial method involves the hydrolysis of cyclohexanone, which is carried out using strong acids or alkalis.

The hydrolysis process typically involves the reaction of cyclohexanone with water in the presence of a catalyst, such as sulfuric acid or hydrochloric acid. The reaction is exothermic and requires careful control of temperature and pressure to ensure the desired product is obtained. The resulting 1,4-Cyclohexanediol is then purified through crystallization or distillation.

Applications of 1,4-Cyclohexanediol

1,4-Cyclohexanediol finds extensive use in the production of polyesters, which are used in textiles, packaging materials, and engineering plastics. It is also a key component in the synthesis of polyurethanes, which are used in foams, adhesives, and coatings. Additionally, 1,4-Cyclohexanediol is used in the production of resins, which are used in paints, varnishes, and lacquers.

The compound's versatility and reactivity make it an essential intermediate in the pharmaceutical industry, where it is used in the synthesis of certain drugs and intermediates. Moreover, 1,4-Cyclohexanediol is used in the production of dyes, solvents, and other specialty chemicals.

Health and Safety Considerations

1,4-Cyclohexanediol is considered hazardous due to its potential to cause irritation to the skin, eyes, and respiratory system. It is also toxic if ingested or inhaled. Therefore, proper handling and safety measures are crucial when working with this chemical.

Workers handling 1,4-Cyclohexanediol should wear appropriate personal protective equipment, such as gloves, goggles, and respiratory protection. The compound should be stored in a cool, dry place, away from incompatible materials and sources of ignition. In case of accidental exposure, immediate medical attention should be sought.

Environmental Impact

The environmental impact of 1,4-Cyclohexanediol is primarily related to its potential to contaminate water sources. The compound is not biodegradable and can persist in the environment for an extended period. Therefore, proper waste management and treatment are essential to minimize its impact on ecosystems.

Regulatory agencies around the world have set limits on the discharge of 1,4-Cyclohexanediol into water bodies. Industries producing or using this chemical must comply with these regulations to ensure the protection of the environment and public health.

Regulatory Status

1,4-Cyclohexanediol is subject to various regulations and standards, depending on the country and the specific application. In the European Union, the substance is classified as hazardous and is subject to the REACH (Registration, Evaluation, Authorisation, and Restriction of Chemicals) regulation. In the United States, the chemical is regulated under the Toxic Substances Control Act (TSCA).

Producers and users of 1,4-Cyclohexanediol must comply with these regulations, which include providing safety data sheets, conducting risk assessments, and ensuring proper handling and disposal of the chemical.

Conclusion

1,4-Cyclohexanediol, with its CAS number 556-48-9, is a versatile and widely used chemical in various industries. Its synthesis, properties, applications, and safety considerations are crucial aspects that need to be understood by anyone involved in its production or use. By adhering to the appropriate regulations and safety measures, the environmental and health impacts of 1,4-Cyclohexanediol can be minimized, ensuring its continued use in a responsible manner.

Keywords: 1,4-Cyclohexanediol, CAS 556-48-9, chemical properties, synthesis, applications, health and safety, environmental impact, regulatory status.