The Ultimate Guide to 4-Fluorobenzoic Acid CAS 456-22-4： Everything You Need to Know

Abstract

This article provides a comprehensive guide to 4-Fluorobenzoic Acid, CAS 456-22-4, offering an in-depth look into its properties, uses, safety considerations, and applications. It covers the chemical structure, physical and chemical properties, synthesis methods, applications in various industries, safety and handling guidelines, and regulatory information, making it an essential resource for anyone interested in this compound.

Introduction to 4-Fluorobenzoic Acid

4-Fluorobenzoic Acid, with the chemical formula C6H4FO2, is a derivative of benzoic acid where a fluorine atom is substituted for a hydrogen atom on the benzene ring. It is a white crystalline solid that is widely used in various industrial applications due to its unique properties. This guide aims to provide a detailed overview of 4-Fluorobenzoic Acid, covering all aspects necessary for understanding its significance and usage.

Chemical Structure and Physical Properties

The chemical structure of 4-Fluorobenzoic Acid consists of a benzene ring with a fluorine atom attached to the fourth position. This substitution introduces a slight polarity to the molecule, which affects its solubility and reactivity. The physical properties of 4-Fluorobenzoic Acid include a melting point of approximately 69-70°C and a boiling point of around 224-225°C. It is slightly soluble in water and more soluble in organic solvents such as ethanol and acetone.

Synthesis Methods

The synthesis of 4-Fluorobenzoic Acid can be achieved through various methods, including the direct fluorination of benzoic acid, the reaction of 4-fluorobenzaldehyde with sodium hydroxide, and the reaction of 4-fluorobenzyl alcohol with chloroacetic acid. Each method has its advantages and limitations, and the choice of synthesis route depends on the scale of production and the desired purity of the final product.

Applications in Various Industries

4-Fluorobenzoic Acid finds extensive use in various industries due to its unique properties. It is commonly used as a flame retardant in plastics and textiles, a stabilizer in rubber products, and a preservative in food and pharmaceuticals. Additionally, it serves as a precursor for the synthesis of other fluorinated compounds, which are used in electronics, pharmaceuticals, and agrochemicals.

Safety and Handling Guidelines

Handling 4-Fluorobenzoic Acid requires careful adherence to safety guidelines due to its potential hazards. It is a corrosive substance that can cause severe burns to the skin and eyes. When working with 4-Fluorobenzoic Acid, it is essential to wear appropriate personal protective equipment, such as gloves, goggles, and lab coats. The substance should be stored in a cool, dry place, away from incompatible materials and sources of ignition.

Regulatory Information

4-Fluorobenzoic Acid is subject to various regulations and standards, depending on its use and the country of operation. In the United States, it is regulated under the Toxic Substances Control Act (TSCA) and the Occupational Safety and Health Administration (OSHA) standards. Compliance with these regulations is crucial for manufacturers, distributors, and users of the compound.

Conclusion

The Ultimate Guide to 4-Fluorobenzoic Acid CAS 456-22-4: Everything You Need to Know serves as a comprehensive resource for understanding the properties, uses, safety considerations, and regulatory aspects of this compound. By covering all these aspects, the guide provides a valuable reference for scientists, engineers, and professionals in various industries that utilize 4-Fluorobenzoic Acid.

Keywords: 4-Fluorobenzoic Acid, CAS 456-22-4, chemical structure, physical properties, synthesis methods, applications, safety guidelines, regulatory information