1-Naphthylacetamide CAS 86-86-2： The Ultimate Resource for Researchers and Chemists

Abstract

This article provides an in-depth exploration of 1-Naphthylacetamide CAS 86-86-2, a crucial compound in the field of chemistry and research. It serves as an ultimate resource for both researchers and chemists, offering insights into its properties, applications, synthesis methods, safety considerations, and its role in various chemical reactions. The article aims to provide a comprehensive understanding of this compound, highlighting its significance in the scientific community.

Introduction to 1-Naphthylacetamide CAS 86-86-2

1-Naphthylacetamide, with the chemical formula C11H9NO, is a derivative of naphthalene and acetic acid. It is commonly referred to by its CAS number, 86-86-2. This compound has gained significant attention due to its versatile applications in organic synthesis, pharmaceuticals, and materials science. The article delves into the various aspects of 1-Naphthylacetamide, making it an invaluable resource for anyone working in these fields.

Properties of 1-Naphthylacetamide CAS 86-86-2

1-Naphthylacetamide is a white crystalline solid that is sparingly soluble in water but readily soluble in organic solvents such as ethanol and acetone. It has a melting point of approximately 80-82°C and a boiling point of around 285°C. These physical properties make it a valuable compound for various applications, including its use as a precursor in the synthesis of pharmaceuticals and dyes.

Applications of 1-Naphthylacetamide CAS 86-86-2

One of the primary applications of 1-Naphthylacetamide is in the synthesis of pharmaceuticals. It serves as a key intermediate in the production of several drugs, including analgesics, antipyretics, and anti-inflammatory agents. Additionally, it is used in the synthesis of dyes and pigments, where its unique chemical properties contribute to the development of vibrant and durable colors. Furthermore, 1-Naphthylacetamide finds applications in materials science, particularly in the development of novel polymers and coatings.

Synthesis Methods of 1-Naphthylacetamide CAS 86-86-2

The synthesis of 1-Naphthylacetamide can be achieved through various methods, each with its own advantages and limitations. One common approach involves the reaction of naphthalene with chloroacetic acid in the presence of a base, followed by neutralization and recrystallization. Another method involves the reaction of naphthalene with acetic anhydride in the presence of a catalyst. These synthesis methods are well-documented and provide researchers with a solid foundation for the production of 1-Naphthylacetamide.

Safety Considerations for 1-Naphthylacetamide CAS 86-86-2

As with any chemical compound, safety considerations are paramount when working with 1-Naphthylacetamide. It is classified as a hazardous substance due to its potential to cause irritation to the skin, eyes, and respiratory system. Proper handling, storage, and disposal procedures are essential to minimize the risk of exposure. Researchers and chemists should always wear appropriate personal protective equipment (PPE) and follow established safety protocols when handling this compound.

Role of 1-Naphthylacetamide CAS 86-86-2 in Chemical Reactions

1-Naphthylacetamide plays a crucial role in various chemical reactions, acting as a versatile intermediate. It is involved in the synthesis of esters, amides, and other organic compounds. The unique structure of 1-Naphthylacetamide allows it to participate in nucleophilic substitution, electrophilic aromatic substitution, and other important reactions. Its ability to undergo these transformations makes it an indispensable tool in the arsenal of organic chemists.

Conclusion

In conclusion, 1-Naphthylacetamide CAS 86-86-2 is a highly valuable compound in the fields of chemistry and research. Its diverse applications, synthesis methods, and unique chemical properties make it an essential resource for both researchers and chemists. By providing a comprehensive overview of this compound, this article aims to serve as a guide for those working with 1-Naphthylacetamide, ensuring safe and effective utilization of this versatile chemical.

Keywords: 1-Naphthylacetamide, CAS 86-86-2, organic synthesis, pharmaceuticals, dyes, safety considerations, chemical reactions