Cis-3-Hexenyl Salicylate CAS 65405-77-8: The Ultimate Guide to Its Uses and Benefits

February 5, 2025

Abstract

This article provides an in-depth guide to Cis-3-Hexenyl Salicylate, CAS 65405-77-8, exploring its various uses and benefits. From its chemical properties and synthesis methods to its applications in the cosmetic, pharmaceutical, and food industries, this comprehensive guide aims to offer readers a thorough understanding of this versatile compound.

Introduction to Cis-3-Hexenyl Salicylate

Cis-3-Hexenyl Salicylate, with the chemical formula C10H14O3, is a synthetic organic compound that belongs to the ester family. It is known for its fruity, floral, and citrusy aroma, making it a popular ingredient in perfumery and flavoring. This guide will delve into the various aspects of Cis-3-Hexenyl Salicylate, including its synthesis, properties, and applications.

Chemical Properties and Synthesis

Cis-3-Hexenyl Salicylate is a colorless to pale yellow liquid with a characteristic fruity odor. It has a melting point of approximately 30-32°C and a boiling point of around 230-234°C. The compound is soluble in organic solvents such as ethanol, acetone, and ether but is only slightly soluble in water.

The synthesis of Cis-3-Hexenyl Salicylate typically involves the esterification of 3-hexenyl alcohol with salicylic acid. This reaction can be carried out using various catalysts, such as sulfuric acid or hydrochloric acid, and is often conducted under reflux conditions to ensure complete reaction.

Applications in Perfumery

Cis-3-Hexenyl Salicylate is widely used in the perfume industry due to its pleasant aroma. It is often found in floral and citrus-based fragrances, contributing to the creation of fresh, vibrant scents. The compound's ability to blend well with other esters and alcohols makes it a versatile ingredient in perfumery.

In addition to its use in fragrances, Cis-3-Hexenyl Salicylate is also employed in the production of flavorings for food and beverages. Its fruity and floral notes can enhance the taste of various products, such as fruit juices, confectionery, and soft drinks.

Pharmaceutical Applications

Cis-3-Hexenyl Salicylate has potential applications in the pharmaceutical industry, primarily due to its anti-inflammatory properties. The compound is believed to have analgesic and anti-inflammatory effects, making it a candidate for the development of new medications for the treatment of pain and inflammation.

Research is ongoing to explore the full potential of Cis-3-Hexenyl Salicylate in pharmaceutical applications. Preliminary studies suggest that the compound could be used in the treatment of various inflammatory conditions, such as arthritis and inflammatory bowel disease.

Food Industry Uses

In the food industry, Cis-3-Hexenyl Salicylate is used as a flavoring agent to enhance the taste of various products. Its fruity and floral notes can be particularly beneficial in the production of fruit-based desserts, jams, and jellies. The compound is also used in the production of soft drinks and alcoholic beverages, where it contributes to the creation of refreshing and aromatic flavors.

It is important to note that the use of Cis-3-Hexenyl Salicylate in food products is regulated by various food safety authorities. The compound must meet specific quality and safety standards to ensure it is safe for consumption.

Environmental Impact and Safety Considerations

Cis-3-Hexenyl Salicylate is considered a low-hazard compound, with a low acute toxicity and no evidence of carcinogenicity. However, it is important to handle the compound with care, as it can be irritating to the skin and eyes. Proper safety measures, such as wearing protective gloves and goggles, should be taken when working with this substance.

In terms of environmental impact, Cis-3-Hexenyl Salicylate is biodegradable and has a low potential for bioaccumulation. However, it is essential to dispose of the compound properly to minimize its impact on the environment.

Conclusion

Cis-3-Hexenyl Salicylate, CAS 65405-77-8, is a versatile compound with a wide range of applications in perfumery, pharmaceuticals, and the food industry. Its pleasant aroma, anti-inflammatory properties, and ability to enhance flavors make it a valuable ingredient in various products. As research continues to explore its potential, Cis-3-Hexenyl Salicylate is poised to play an even more significant role in the future.

Keywords: Cis-3-Hexenyl Salicylate, CAS 65405-77-8, ester, perfumery, pharmaceuticals, food industry, anti-inflammatory, flavoring agent

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