Cobamamide, with the CAS number 13870 - 90 - 1, is a vitamin B12 analog. It is an important coenzyme form of vitamin B12, which participates in the methionine synthesis pathway. The product is factory - supplied and comes at the best price.
Chemical Formula: C72H100CoN18O17P
Molecular Weight: Approximately 1579.6 g/mol
Appearance: Usually a red crystalline powder
Solubility: It is soluble in water, slightly soluble in ethanol, and insoluble in acetone, ether, and chloroform.
Medical Field: Cobamamide plays a crucial role in the treatment of megaloblastic anemia. It participates in the synthesis of nucleic acids, proteins, and lipids, and can promote the maturation of red blood cells. Moreover, it is also used for peripheral neuropathy. It can nourish nerve cells, improve nerve conduction velocity, and relieve symptoms such as numbness, pain, and weakness in the extremities.
Healthcare Products: As a dietary supplement, it can help maintain the normal function of the nervous system and hematopoietic system. For people with a vegetarian diet or those with poor absorption of vitamin B12, it can be an effective way to supplement this important nutrient.
Medical Use: When used in the medical field, the dosage is usually determined by a doctor based on the patient's age, condition, and other factors. Generally, for adults with megaloblastic anemia, the oral dosage may be 0.5 - 1.5 mg per day, divided into several doses. For peripheral neuropathy, the dosage may vary, but it is usually in the range of 0.25 - 0.5 mg per day. It is recommended to take it after meals to reduce gastrointestinal discomfort.
Healthcare Use: As a dietary supplement, the common recommended dosage is 0.1 - 0.5 mg per day. It can be taken directly with water. However, it is always advisable to consult a healthcare professional before starting any new supplement regimen.
Case 1: Megaloblastic Anemia Treatment
A 60 - year - old female patient was diagnosed with megaloblastic anemia. Her symptoms included fatigue, dizziness, and shortness of breath. After being prescribed cobamamide at a dosage of 1 mg per day, combined with folic acid treatment, her hemoglobin level gradually increased. After 3 months of treatment, her anemia symptoms were significantly improved, and her overall physical condition also recovered. Her energy levels increased, and the dizziness and shortness of breath symptoms almost disappeared.
Case 2: Peripheral Neuropathy Relief
A 45 - year - old male patient suffered from diabetic peripheral neuropathy. He had persistent numbness and pain in his feet. After taking cobamamide at a dosage of 0.5 mg per day for 2 months, he reported a significant reduction in pain and numbness. His nerve conduction velocity also improved, as measured by nerve function tests. This indicates that cobamamide can effectively nourish nerve cells and relieve the symptoms of peripheral neuropathy.
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