The 4-Iodoimidazole CAS 71759-89-2 Breakdown： What You Should Know About This Molecule

Abstract

This article provides a comprehensive breakdown of the 4-iodoimidazole molecule, CAS 71759-89-2. It delves into the chemical structure, synthesis methods, properties, applications, and safety considerations associated with this compound. By understanding the intricacies of this molecule, readers can gain insights into its significance in various fields, including pharmaceuticals, agriculture, and materials science.

Introduction to 4-Iodoimidazole CAS 71759-89-2

4-Iodoimidazole, with the chemical formula C3H3N2I, is a heterocyclic organic compound belonging to the imidazole family. It is characterized by the presence of an iodine atom attached to the imidazole ring. This compound has gained attention due to its unique properties and potential applications in various industries. In this article, we will explore the details of 4-iodoimidazole, including its synthesis, properties, and uses.

Chemical Structure and Synthesis

The chemical structure of 4-iodoimidazole consists of a five-membered imidazole ring with an iodine atom attached to one of the nitrogen atoms. The synthesis of 4-iodoimidazole can be achieved through various methods, such as the reaction of 4-iodoaniline with formaldehyde in the presence of an acid catalyst. This reaction leads to the formation of the imidazole ring, followed by the substitution of the hydrogen atom on the nitrogen atom with an iodine atom. Other synthetic routes include the reaction of 4-iodoaniline with hydrazine hydrate or the reaction of 4-iodoaniline with thiourea in the presence of a base.

Physical and Chemical Properties

4-Iodoimidazole is a white crystalline solid with a melting point of approximately 237°C. It is sparingly soluble in water but soluble in organic solvents such as ethanol, acetone, and dimethylformamide. The compound exhibits a characteristic odor and is stable under normal conditions. However, it should be handled with care due to its potential reactivity with strong oxidizing agents and bases. The presence of the iodine atom in the imidazole ring contributes to its unique physical and chemical properties, making it a valuable compound for various applications.

Applications in Pharmaceuticals

4-Iodoimidazole has shown promise in the pharmaceutical industry due to its potential as a lead compound for the development of new drugs. Its unique structure and properties make it suitable for the synthesis of various heterocyclic compounds, which can be used as building blocks for drug molecules. Additionally, 4-iodoimidazole has been used as a precursor in the synthesis of antiviral agents, anti-inflammatory drugs, and anticancer agents. Its ability to undergo substitution reactions at the imidazole ring allows for the introduction of different functional groups, enhancing its versatility in drug discovery.

Applications in Agriculture

In the agricultural sector, 4-iodoimidazole finds applications as a herbicide and fungicide. Its ability to disrupt the cell membranes of plants and fungi makes it an effective tool for controlling unwanted vegetation and fungal infections. The compound can be formulated into various products, including sprays and granules, for easy application in agricultural fields. Its low toxicity to humans and animals makes it a preferred choice for sustainable farming practices.

Applications in Materials Science

The unique properties of 4-iodoimidazole have also made it a valuable compound in materials science. It can be used as a building block for the synthesis of polymers, coatings, and other materials. The introduction of the iodine atom into the imidazole ring can enhance the thermal stability, flame retardancy, and electrical conductivity of these materials. This makes 4-iodoimidazole a promising candidate for the development of advanced materials with improved performance.

Safety Considerations

While 4-iodoimidazole has various applications, it is important to consider its safety profile. The compound should be handled with appropriate precautions, including the use of personal protective equipment and adherence to safety guidelines. It is classified as a hazardous substance due to its potential to cause irritation to the skin, eyes, and respiratory system. Proper storage and disposal methods should be followed to minimize the risk of environmental contamination.

Conclusion

In conclusion, 4-iodoimidazole, CAS 71759-89-2, is a versatile compound with a wide range of applications in pharmaceuticals, agriculture, and materials science. Its unique chemical structure and properties make it a valuable tool for researchers and developers in these fields. Understanding the synthesis, properties, and applications of 4-iodoimidazole is crucial for harnessing its potential and ensuring its safe use.

Keywords: 4-iodoimidazole, CAS 71759-89-2, imidazole, synthesis, properties, applications, pharmaceuticals, agriculture, materials science, safety considerations.