The Ultimate Guide to Ethyl 3-Amino-3-Thioxopropanoate CAS 13621-50-6： Everything You Need to Know

Abstract

This article provides a comprehensive guide to Ethyl 3-Amino-3-Thioxopropanoate, also known as CAS 13621-50-6. It delves into the chemical properties, synthesis methods, applications, safety considerations, and regulatory information surrounding this compound. By exploring these aspects, the article aims to offer a thorough understanding of Ethyl 3-Amino-3-Thioxopropanoate, making it an essential resource for researchers, chemists, and anyone interested in this chemical substance.

Introduction to Ethyl 3-Amino-3-Thioxopropanoate

Ethyl 3-Amino-3-Thioxopropanoate, with the chemical formula C4H7NO2S, is a compound that belongs to the thioester class. It is commonly referred to by its CAS number, 13621-50-6. This compound is of significant interest in various fields, including organic synthesis, pharmaceuticals, and agrochemicals. The following sections will explore the different aspects of Ethyl 3-Amino-3-Thioxopropanoate, providing a comprehensive understanding of its characteristics and uses.

Chemical Properties

Ethyl 3-Amino-3-Thioxopropanoate is a colorless to pale yellow liquid with a pungent odor. It is soluble in organic solvents such as ethanol, acetone, and dichloromethane but is not soluble in water. The compound has a melting point of approximately 70-72°C and a boiling point of around 160-162°C. Its molecular weight is 137.18 g/mol, and it contains a sulfur atom, which is characteristic of thioesters. The presence of the amino group (-NH2) and the thioxo group (-SO-) in its structure contributes to its unique chemical properties.

Synthesis Methods

The synthesis of Ethyl 3-Amino-3-Thioxopropanoate can be achieved through various methods, including the reaction of ethyl chloroacetate with thiourea and subsequent hydrolysis. Another common synthesis method involves the reaction of ethyl chloroacetate with sodium sulfide followed by the addition of ammonia. These synthetic routes require careful control of reaction conditions to ensure the desired product is obtained. The choice of synthesis method often depends on the scale of production and the specific requirements of the application.

Applications

Ethyl 3-Amino-3-Thioxopropanoate finds applications in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. In the pharmaceutical industry, it serves as an intermediate in the production of various drugs, including antibiotics and antiviral agents. In agrochemicals, it is used as a precursor for herbicides and fungicides. Additionally, Ethyl 3-Amino-3-Thioxopropanoate is employed in the synthesis of dyes, polymers, and other specialty chemicals.

Safety Considerations

Handling Ethyl 3-Amino-3-Thioxopropanoate requires appropriate safety measures due to its potential hazards. The compound is toxic if ingested, inhaled, or absorbed through the skin. It can cause irritation to the eyes, skin, and respiratory system. Therefore, it is crucial to wear protective equipment, such as gloves, goggles, and a lab coat, when working with this substance. Proper ventilation and adherence to safety protocols are essential to minimize the risk of exposure.

Regulatory Information

Ethyl 3-Amino-3-Thioxopropanoate is subject to regulatory control in many countries. The European Union, for instance, has established regulations for the production, import, and use of this compound. Compliance with these regulations is mandatory for manufacturers and users to ensure the safe handling and disposal of Ethyl 3-Amino-3-Thioxopropanoate. It is essential to consult the relevant regulatory authorities for specific guidelines and requirements.

Conclusion

In conclusion, Ethyl 3-Amino-3-Thioxopropanoate, with the CAS number 13621-50-6, is a versatile compound with a wide range of applications. This guide has provided an overview of its chemical properties, synthesis methods, applications, safety considerations, and regulatory information. Understanding these aspects is crucial for researchers, chemists, and anyone involved in the handling or use of this compound. By following the guidelines and regulations outlined in this guide, one can ensure the safe and responsible use of Ethyl 3-Amino-3-Thioxopropanoate.

Keywords: Ethyl 3-Amino-3-Thioxopropanoate, CAS 13621-50-6, chemical properties, synthesis methods, applications, safety considerations, regulatory information