Unlock the Power of CAS 141-23-1: The Ultimate Guide to 12-Hydroxy Stearic Acid Methyl Ester

February 3, 2025

Abstract

This article provides a comprehensive guide to 12-Hydroxy Stearic Acid Methyl Ester (CAS 141-23-1), commonly known as CAS 141-23-1. It delves into the properties, applications, synthesis methods, safety considerations, and regulatory aspects of this chemical compound. By exploring these facets, the article aims to unlock the full potential of CAS 141-23-1, offering valuable insights for researchers, manufacturers, and users in various industries.

Introduction to 12-Hydroxy Stearic Acid Methyl Ester (CAS 141-23-1)

12-Hydroxy Stearic Acid Methyl Ester, with the chemical formula C21H42O3, is a type of fatty acid ester derived from stearic acid. It is widely recognized by its CAS number 141-23-1. This compound finds applications in various industries, including pharmaceuticals, cosmetics, and food, due to its unique properties and benefits.

Properties of 12-Hydroxy Stearic Acid Methyl Ester

12-Hydroxy Stearic Acid Methyl Ester is a white solid with a melting point of approximately 45-50°C. It is soluble in organic solvents such as ethanol, acetone, and chloroform but has limited solubility in water. The presence of the hydroxyl group in the molecule contributes to its hydrophilic nature, making it suitable for use in emulsions and formulations.

Applications of 12-Hydroxy Stearic Acid Methyl Ester

One of the primary applications of 12-Hydroxy Stearic Acid Methyl Ester is in the pharmaceutical industry. It is used as a lubricant in tablet formulations, improving the flowability and compressibility of the active ingredients. Additionally, it serves as a stabilizer in emulsions, preventing separation of oil and water phases.

In the cosmetics industry, 12-Hydroxy Stearic Acid Methyl Ester is utilized as an emulsifier and thickener in creams, lotions, and shampoos. Its ability to improve the texture and stability of these products makes it a valuable ingredient. Moreover, it is employed in the food industry as an emulsifier and stabilizer in baked goods, confectionery, and dairy products.

Synthesis of 12-Hydroxy Stearic Acid Methyl Ester

The synthesis of 12-Hydroxy Stearic Acid Methyl Ester involves the reaction between 12-hydroxy stearic acid and methanol in the presence of a catalyst. The process typically requires heating the reactants under reflux conditions to facilitate the esterification reaction. The catalyst used can be a strong acid, such as sulfuric acid, or an enzyme, such as lipase.

The reaction yields a mixture of 12-hydroxy stearic acid methyl ester and unreacted 12-hydroxy stearic acid. To obtain a pure product, the mixture is subjected to purification techniques such as crystallization or distillation. The purity of the final product is crucial for its applications in various industries.

Safety Considerations of 12-Hydroxy Stearic Acid Methyl Ester

12-Hydroxy Stearic Acid Methyl Ester is considered safe for use in pharmaceuticals, cosmetics, and food applications. However, it is important to handle it with care due to its potential skin and eye irritation. Adequate personal protective equipment, such as gloves and goggles, should be worn during handling and processing.

The acute toxicity of 12-Hydroxy Stearic Acid Methyl Ester is low, with a LD50 value of around 5 g/kg in rats. However, long-term exposure to high concentrations may have adverse effects on the respiratory system. Therefore, it is essential to follow recommended exposure limits and guidelines to ensure the safety of workers and consumers.

Regulatory Aspects of 12-Hydroxy Stearic Acid Methyl Ester

12-Hydroxy Stearic Acid Methyl Ester is regulated by various authorities, including the Food and Drug Administration (FDA) and the European Union (EU). The FDA has approved its use as a food additive, and the EU has classified it as a food contact substance. These regulations ensure the safety and quality of products containing this compound.

The regulatory authorities also establish guidelines for the maximum allowable concentration of 12-Hydroxy Stearic Acid Methyl Ester in different applications. Adhering to these guidelines is crucial for manufacturers and users to comply with legal requirements and maintain product safety.

Conclusion

In conclusion, 12-Hydroxy Stearic Acid Methyl Ester (CAS 141-23-1) is a versatile chemical compound with a wide range of applications in various industries. This article has provided an in-depth analysis of its properties, synthesis methods, safety considerations, and regulatory aspects. By understanding these factors, researchers, manufacturers, and users can unlock the full potential of CAS 141-23-1 and utilize it effectively in their respective fields.

Keywords: 12-Hydroxy Stearic Acid Methyl Ester, CAS 141-23-1, fatty acid ester, applications, synthesis, safety, regulatory aspects

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