Don't Miss Out： The Essential Info on 2-(N-Ethyl-m-Toluidino)ethano CAS 91-88-3 You Need to Know!

Abstract

This article provides a comprehensive overview of the chemical compound 2-(N-Ethyl-m-Toluidino)ethano, also known as CAS 91-88-3. It delves into its chemical properties, synthesis methods, applications, safety considerations, regulatory information, and environmental impact. By exploring these aspects, the article aims to offer essential information for those interested in understanding this compound in detail.

Chemical Properties of 2-(N-Ethyl-m-Toluidino)ethano

2-(N-Ethyl-m-Toluidino)ethano, with the CAS number 91-88-3, is an organic compound belonging to the class of amines. It is characterized by a benzene ring with a methyl group and an ethyl group attached to the para position, along with an ethylamine substituent. This compound has a molecular formula of C₉H₁₃N and a molecular weight of 137.21 g/mol. The chemical structure of 2-(N-Ethyl-m-Toluidino)ethano is complex, and it exhibits various physical and chemical properties that make it useful in different applications.

One of the key properties of 2-(N-Ethyl-m-Toluidino)ethano is its solubility in organic solvents. It is sparingly soluble in water but highly soluble in organic solvents such as ethanol, acetone, and dichloromethane. This property makes it convenient for synthesis and purification processes. Additionally, the compound has a melting point of approximately 68-70°C and a boiling point of around 285-287°C, which are important parameters for its handling and storage.

The chemical reactivity of 2-(N-Ethyl-m-Toluidino)ethano is another crucial aspect. It can undergo various chemical reactions, including nucleophilic substitution, electrophilic aromatic substitution, and reduction reactions. These reactions are essential for its synthesis and modification, allowing for the creation of a wide range of derivatives with different functionalities.

Synthesis Methods of 2-(N-Ethyl-m-Toluidino)ethano

The synthesis of 2-(N-Ethyl-m-Toluidino)ethano can be achieved through several methods, each with its own advantages and limitations. One common synthesis method involves the reaction of 4-methylbenzenesulfonyl chloride with ethylamine in the presence of a base, such as pyridine or triethylamine. This reaction leads to the formation of the desired compound, along with by-products that need to be separated and purified.

Another synthesis method involves the reaction of 4-methylbenzenesulfonyl chloride with N-ethylbenzylamine in the presence of a base. This method is advantageous as it produces a higher yield of the desired compound and requires fewer steps compared to the previous method. However, it may require more stringent reaction conditions and purification procedures.

A third synthesis method involves the reaction of 4-methylbenzenesulfonyl chloride with N-ethylbenzylamine in the presence of a catalytic amount of a metal catalyst, such as palladium or platinum. This method offers a more efficient and environmentally friendly approach, as it reduces the need for harsh reaction conditions and minimizes the formation of by-products.

Each synthesis method has its own set of considerations, including reaction time, temperature, and the choice of reagents and solvents. The selection of the appropriate synthesis method depends on the desired scale of production, cost, and environmental impact.

Applications of 2-(N-Ethyl-m-Toluidino)ethano

2-(N-Ethyl-m-Toluidino)ethano finds applications in various fields due to its unique chemical properties. One of the primary applications is in the pharmaceutical industry, where it serves as a precursor for the synthesis of pharmaceutical intermediates and active pharmaceutical ingredients (APIs). Its ability to undergo various chemical reactions allows for the creation of compounds with desired therapeutic properties.

In the field of materials science, 2-(N-Ethyl-m-Toluidino)ethano is used as a building block for the synthesis of polymers and organic electronic materials. Its presence in these materials can enhance their electrical conductivity, optical properties, and thermal stability.

Furthermore, the compound finds applications in the agrochemical industry, where it is used as an intermediate for the synthesis of herbicides and pesticides. Its ability to undergo substitution reactions makes it a versatile starting material for the development of new agrochemicals.

The versatility of 2-(N-Ethyl-m-Toluidino)ethano also extends to the field of analytical chemistry, where it can be used as a standard or reference material for the calibration of analytical instruments. Its known chemical properties and purity make it a reliable choice for such applications.

Safety Considerations for 2-(N-Ethyl-m-Toluidino)ethano

Handling and storing 2-(N-Ethyl-m-Toluidino)ethano require careful consideration of its safety properties. The compound is considered hazardous and poses certain risks to human health and the environment. It is classified as a toxic substance and can cause irritation to the skin, eyes, and respiratory system upon contact.

To ensure safe handling, it is essential to wear appropriate personal protective equipment (PPE), such as gloves, goggles, and lab coats. Adequate ventilation is also crucial to prevent the accumulation of vapors in enclosed spaces.

In terms of storage, 2-(N-Ethyl-m-Toluidino)ethano should be kept in a cool, dry place away from direct sunlight and incompatible materials. It should be stored in tightly sealed containers to prevent evaporation and potential exposure to air.

Accidental spills or leaks should be handled promptly and according to established procedures. Proper waste disposal methods should be followed to minimize environmental impact.

Regulatory Information and Environmental Impact

2-(N-Ethyl-m-Toluidino)ethano is subject to various regulations and guidelines, both at the national and international levels. These regulations aim to ensure the safe handling, use, and disposal of the compound to protect human health and the environment.

In many countries, the production, import, and export of 2-(N-Ethyl-m-Toluidino)ethano are regulated by specific laws and regulations. These regulations may include restrictions on the quantity produced or imported, as well as requirements for labeling and packaging.

The environmental impact of 2-(N-Ethyl-m-Toluidino)ethano is also a concern. The compound can be toxic to aquatic organisms and may persist in the environment for an extended period. Therefore, proper waste management and disposal methods are crucial to minimize its impact on ecosystems.

Conclusion
In conclusion, 2-(N-Ethyl-m-Toluidino)ethano, with the CAS number 91-88-3, is a versatile organic compound with various applications in the pharmaceutical, materials science, and agrochemical industries. Understanding its chemical properties, synthesis methods, applications, safety considerations, regulatory information, and environmental impact is essential for those involved in its production, handling, and use. By considering these factors, stakeholders can ensure the safe and responsible use of this compound, contributing to its continued relevance in various fields.

Keywords: 2-(N-Ethyl-m-Toluidino)ethano, CAS 91-88-3, chemical properties, synthesis methods, applications, safety considerations, regulatory information, environmental impact