The product named "Factory Supply 4-Iodoaniline CAS 540-37-4 With Good Price" is a chemical compound. The CAS number 540 - 37 - 4 uniquely identifies this chemical. 4 - Iodoaniline is an organic compound with the molecular formula C₆H₆IN. It has a molecular weight of approximately 235.02 g/mol.
Physically, 4 - Iodoaniline appears as a white to light - yellow crystalline powder. It has a melting point in the range of 56 - 59°C. It is sparingly soluble in water but soluble in common organic solvents such as ethanol, ether, and chloroform. The purity of our factory - supplied 4 - Iodoaniline is carefully controlled to meet high - quality standards, usually with a purity level of over 98%.
4 - Iodoaniline has a wide range of applications in various fields. In the pharmaceutical industry, it serves as an important intermediate for the synthesis of many drugs. It can be used to introduce the iodo - aniline group into the molecular structure of drugs, which may enhance the biological activity or modify the pharmacological properties of the final drug products.
In the field of organic synthesis, 4 - Iodoaniline is a key building block. It can participate in a variety of chemical reactions, such as coupling reactions. For example, it can be used in the Suzuki - Miyaura coupling reaction, where it reacts with arylboronic acids to form biaryls, which are important structures in many functional materials and biologically active compounds.
It also has applications in the dye industry. Some dyes are synthesized using 4 - Iodoaniline as a starting material, and the iodine atom in its structure can affect the color and light - fastness properties of the dyes.
When using 4 - Iodoaniline, proper safety precautions should be taken. Always wear appropriate personal protective equipment, including safety glasses, gloves, and a lab coat.
For laboratory - scale reactions, accurately weigh the required amount of 4 - Iodoaniline using a precision balance. It is usually added to the reaction mixture under appropriate reaction conditions, such as in an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation.
The reaction temperature and reaction time should be carefully controlled according to the specific reaction requirements. After the reaction is completed, standard purification methods such as recrystallization or column chromatography can be used to obtain the pure product.
Case 1: Pharmaceutical Synthesis
A research group was working on the synthesis of a new anti - cancer drug. They used 4 - Iodoaniline as an intermediate. First, they carried out a Buchwald - Hartwig amination reaction with an appropriate aryl halide in the presence of a palladium catalyst and a base. The reaction was carried out in toluene at 100°C for 12 hours under a nitrogen atmosphere. After purification by column chromatography, they obtained an important intermediate with a yield of 70%. This intermediate was further modified and finally led to the successful synthesis of the anti - cancer drug candidate.
Case 2: Organic Material Synthesis
In a project for synthesizing a new organic semiconductor material, 4 - Iodoaniline was used in a Stille coupling reaction. It was reacted with a stannyl - substituted aryl compound in the presence of a palladium catalyst in a mixture of dioxane and water at 80°C for 8 hours. The resulting product was a conjugated polymer with good charge - transport properties. After optimizing the reaction conditions, the yield of the polymer was improved to 60%, and the final material showed promising performance in organic field - effect transistors.
If you have any questions or need further information about our Factory Supply 4 - Iodoaniline CAS 540 - 37 - 4, please feel free to contact us.
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