Factory Supply 1,3-Bis(trifluoromethyl)-benzene CAS 402-31-3 User Guide

Table of Contents

• 1. Basic Information and Parameters
• 2. Product Uses
• 3. Product Usage
• 4. Detailed Usage Case Studies
• 5. Contact Information

1. Basic Information and Parameters

The product, Factory Supply 1,3 - Bis(trifluoromethyl)-benzene, has a CAS number of 402 - 31 - 3. It is supplied by the factory with a good price. The chemical formula of 1,3 - Bis(trifluoromethyl)-benzene is C₆H₄(CF₃)₂. Its molecular weight is approximately 226.09 g/mol. The compound appears as a clear, colorless liquid at room temperature. It has a boiling point around 116 - 117 °C and a melting point of about - 35 °C. The density is about 1.38 g/mL at 25 °C. It is insoluble in water but soluble in many organic solvents such as ethanol, ether, and chloroform.

2. Product Uses

1,3 - Bis(trifluoromethyl)-benzene has a wide range of applications in various industries. In the field of organic synthesis, it serves as an important building block. It can be used to introduce trifluoromethyl groups into organic molecules, which can significantly change the physical and chemical properties of the molecules, such as increasing lipophilicity, improving biological activity, and enhancing chemical stability. In the pharmaceutical industry, this compound is used in the synthesis of some drugs. The trifluoromethyl - substituted compounds may have better bioavailability and stronger interaction with biological targets. In the materials science, it can be used in the synthesis of high - performance polymers. The introduction of trifluoromethyl groups can improve the thermal stability, chemical resistance, and surface properties of polymers, making them suitable for applications in aerospace, electronics, and other high - tech fields.

3. Product Usage

When using 1,3 - Bis(trifluoromethyl)-benzene, appropriate safety precautions should be taken. It should be handled in a well - ventilated area or under a fume hood to avoid inhalation of vapors. Wear appropriate personal protective equipment, including safety glasses, gloves, and a lab coat. In organic synthesis reactions, the amount of the compound used should be accurately measured according to the reaction stoichiometry. It is usually added slowly to the reaction system under stirring and controlled temperature conditions. After the reaction, the product should be purified by appropriate methods such as distillation, recrystallization, or chromatography.

4. Detailed Usage Case Studies

Case 1: Pharmaceutical Synthesis

A research team was synthesizing a new anti - cancer drug. They used 1,3 - Bis(trifluoromethyl)-benzene as a key intermediate. The reaction started by reacting 1,3 - Bis(trifluoromethyl)-benzene with a specific amine compound under basic conditions. The reaction was carried out in a solvent of dimethylformamide (DMF) at 80 °C for 12 hours. After the reaction, the product was separated by column chromatography. The introduction of the trifluoromethyl groups from 1,3 - Bis(trifluoromethyl)-benzene improved the lipophilicity of the final drug molecule, which enhanced its ability to penetrate cell membranes and reach the target sites in cancer cells. The in - vitro and in - vivo tests showed that the new drug had better anti - cancer activity compared to the non - trifluoromethyl - substituted analogs.

Case 2: Polymer Synthesis

A materials science group was developing a new type of high - performance polymer for aerospace applications. They copolymerized 1,3 - Bis(trifluoromethyl)-benzene with a diol monomer. The polymerization reaction was carried out in the presence of a catalyst at high temperature under an inert atmosphere. The resulting polymer had excellent thermal stability, with a decomposition temperature above 400 °C. It also showed good chemical resistance to solvents and oxidizing agents. The surface of the polymer was smooth and had low friction coefficient, which was beneficial for reducing air resistance in aerospace applications.

5. Contact Information

If you have any questions or need more information about Factory Supply 1,3 - Bis(trifluoromethyl)-benzene CAS 402 - 31 - 3, please feel free to contact us. Our email address is info@vivalr.com, and our phone number is (86) 15866781826.