Product Name: L-Glutamic Acid α-tert-Butyl Ester
CAS Number: 45120-30-7
Molecular Formula: C9H17NO4
Molecular Weight: 219.24 g/mol
Appearance: White to off-white crystalline powder
Purity: ≥98% (HPLC)
Storage: Store at 2-8°C in a dry, airtight container.
L-Glutamic Acid α-tert-Butyl Ester (CAS 45120-30-7) is widely used in:
Step 1: Weigh the required quantity using a calibrated balance.
Step 2: Dissolve in compatible solvents (e.g., DMF, DMSO) under inert atmosphere.
Step 3: Use in coupling reactions with carbodiimide reagents for peptide bond formation.
Safety Precautions:
Case Study 1: Peptide Drug Synthesis
A pharmaceutical company utilized CAS 45120-30-7 as a protective group in synthesizing a novel ACE inhibitor. The tert-butyl ester group enabled selective deprotection, achieving 92% reaction yield.
Case Study 2: Cosmetic Stabilizer
A skincare brand incorporated 0.5% w/w of this compound in anti-aging serums, improving ingredient stability by 40% under accelerated aging conditions (40°C/75% RH).
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