
Retinoic acid with the CAS number 302 - 79 - 4 is a crucial biochemical compound. It is a derivative of vitamin A and belongs to the family of retinoids. The molecular formula of retinoic acid is C20H28O2, and its molecular weight is approximately 300.43 g/mol.
It typically appears as a yellow to orange - red crystalline powder. The melting point of retinoic acid is around 180 - 181 °C. It is relatively insoluble in water but soluble in organic solvents such as ethanol, chloroform, and acetone. This product is factory - supplied, ensuring a stable source and good price performance.
Medical Field: Retinoic acid plays a vital role in the medical industry. It is widely used in the treatment of acne. It works by regulating the growth and differentiation of skin cells, reducing the formation of acne lesions. Additionally, it has shown great potential in the treatment of certain types of cancer, such as acute promyelocytic leukemia (APL). In APL treatment, retinoic acid can induce the differentiation of immature leukemia cells, leading to their normal development and eventual apoptosis.
Cosmetic Industry: In the cosmetic field, retinoic acid is a popular ingredient in anti - aging products. It can stimulate the production of collagen, which helps to reduce the appearance of fine lines and wrinkles, improve skin texture, and enhance skin elasticity. It also promotes cell turnover, resulting in a smoother and more youthful - looking complexion.
Medical Usage: When used for acne treatment, retinoic acid is usually formulated as a topical cream or gel. It should be applied to the clean and dry affected area of the skin once a day, preferably at night. Start with a low concentration to avoid skin irritation. If you experience redness, peeling, or dryness, reduce the frequency of application or consult a doctor.
In cancer treatment, retinoic acid is administered orally under the strict supervision of medical professionals. The dosage and treatment duration are determined based on the patient's condition, age, and other factors.
Cosmetic Usage: For cosmetic products containing retinoic acid, follow the instructions on the product label. Generally, apply a small amount of the product evenly to the face and neck after cleansing. Avoid applying it to the eye area. Since retinoic acid can increase skin sensitivity to sunlight, it is recommended to use sunscreen during the day.
Acne Treatment Case: A 22 - year - old female suffered from moderate acne on her face. She started using a 0.025% retinoic acid gel once a day at night. In the first two weeks, she experienced mild skin irritation, including redness and peeling. However, after four weeks of continuous use, the number of acne lesions significantly decreased. After three months, her skin became smoother, and the acne problem was largely resolved.
Cancer Treatment Case: A 35 - year - old male was diagnosed with acute promyelocytic leukemia. He was treated with oral retinoic acid as part of the chemotherapy regimen. After one month of treatment, the bone marrow examination showed a significant reduction in the number of immature leukemia cells. With continued treatment for six months, the patient achieved complete remission, and his overall health improved significantly.
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