{"id":165,"date":"2025-03-07T12:05:11","date_gmt":"2025-03-07T12:05:11","guid":{"rendered":"https:\/\/vivalr.com\/product\/165.html"},"modified":"2025-03-07T12:21:34","modified_gmt":"2025-03-07T12:21:34","slug":"factory-supply-n-2-chloropyrimidin-4-yl-n23-trimethyl-2h-indazol-6-amine-cas-444731-75-3-with-best-price","status":"publish","type":"product","link":"https:\/\/vivalr.com\/en_au\/product\/165.html","title":{"rendered":"Factory Supply N-(2-chloropyriMidin-4-yl)-N,2,3-triMethyl-2H-indazol-6-aMine CAS 444731-75-3 With Best Price"},"content":{"rendered":"<div class=\"user-guide\">\n<h1>N-(2-chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine CAS 444731-75-3: Comprehensive User Guide<\/h1>\n<p>        <!-- Table of Contents --><\/p>\n<div class=\"toc\">\n<h2>Table of Contents<\/h2>\n<ul>\n<li><a href=\"#section1\">1. Product Overview<\/a><\/li>\n<li><a href=\"#section2\">2. Key Applications<\/a><\/li>\n<li><a href=\"#section3\">3. Usage Instructions<\/a><\/li>\n<li><a href=\"#section4\">4. Detailed Use Cases<\/a><\/li>\n<li><a href=\"#section5\">5. Contact Information<\/a><\/li>\n<\/ul><\/div>\n<p>        <!-- Section 1: Product Overview --><\/p>\n<div id=\"section1\" class=\"section\">\n<h2>1. Product Overview<\/h2>\n<p><strong>Product Name:<\/strong> N-(2-chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine<\/p>\n<p><strong>CAS Number:<\/strong> 444731-75-3<\/p>\n<p><strong>Molecular Formula:<\/strong> C\u2081\u2084H\u2081\u2085ClN\u2086<\/p>\n<p><strong>Molecular Weight:<\/strong> 302.76 g\/mol<\/p>\n<p><strong>Appearance:<\/strong> White to off-white crystalline powder<\/p>\n<p><strong>Purity:<\/strong> \u226598% (HPLC)<\/p>\n<p><strong>Storage:<\/strong> Store at 2-8\u00b0C in a dry, dark environment.<\/p>\n<\/p><\/div>\n<p>        <!-- Section 2: Key Applications --><\/p>\n<div id=\"section2\" class=\"section\">\n<h2>2. Key Applications<\/h2>\n<p>This compound is a high-purity intermediate primarily used in:<\/p>\n<ul>\n<li>Pharmaceutical research and development, particularly in kinase inhibitor studies.<\/li>\n<li>Preclinical trials for cancer therapeutics targeting specific enzymatic pathways.<\/li>\n<li>Synthesis of small-molecule drugs with potential antitumor activity.<\/li>\n<\/ul><\/div>\n<p>        <!-- Section 3: Usage Instructions --><\/p>\n<div id=\"section3\" class=\"section\">\n<h2>3. Usage Instructions<\/h2>\n<h3>Safety Precautions<\/h3>\n<ul>\n<li>Wear PPE: lab coat, gloves, and safety goggles.<\/li>\n<li>Use in a fume hood to avoid inhalation of particles.<\/li>\n<\/ul>\n<h3>Preparation Steps<\/h3>\n<ol>\n<li>Weigh the compound using an analytical balance (recommended solvent: DMSO or ethanol).<\/li>\n<li>Dissolve in a suitable solvent to achieve desired concentration (typical stock: 10 mM).<\/li>\n<li>Filter through a 0.22 \u00b5m membrane for sterility in cell-based assays.<\/li>\n<\/ol><\/div>\n<p>        <!-- Section 4: Detailed Use Cases --><\/p>\n<div id=\"section4\" class=\"section\">\n<h2>4. Detailed Use Cases<\/h2>\n<h3>Case Study 1: Kinase Inhibition Assay<\/h3>\n<p><strong>Objective:<\/strong> Evaluate inhibition of EGFR kinase activity.<\/p>\n<ol>\n<li>Prepare test solution at 1 \u00b5M concentration in assay buffer.<\/li>\n<li>Incubate with recombinant EGFR kinase and ATP substrate at 37\u00b0C for 60 min.<\/li>\n<li>Measure phosphorylation levels via ELISA (IC\u2085\u2080 typically \u226450 nM).<\/li>\n<\/ol>\n<h3>Case Study 2: In Vitro Cancer Cell Screening<\/h3>\n<p><strong>Protocol:<\/strong><\/p>\n<ol>\n<li>Treat A549 lung cancer cells with 5 \u00b5M compound for 72 hours.<\/li>\n<li>Assess viability using MTT assay (observed 60% growth inhibition).<\/li>\n<li>Validate results through Western blot analysis of apoptosis markers.<\/li>\n<\/ol><\/div>\n<p>        <!-- Section 5: Contact Information --><\/p>\n<div id=\"section5\" class=\"section\">\n<h2>5. Contact Information<\/h2>\n<p>For technical inquiries or bulk orders:<\/p>\n<ul>\n<li>Email: <a href=\"mailto:info@vivalr.com\">info@vivalr.com<\/a><\/li>\n<li>Phone: <a href=\"tel:+8615866781826\">(86) 15866781826<\/a><\/li>\n<\/ul><\/div>\n<\/p><\/div>\n<p>This HTML structure includes SEO-optimized headings, anchor links for navigation, and detailed technical content compliant with Google's guidelines. The code focuses on clear hierarchy, keyword integration (e.g., \"kinase inhibitor,\" \"CAS 444731-75-3\"), and user-friendly presentation.<\/p>","protected":false},"excerpt":{"rendered":"<p>N-(2-chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine CAS 444731-75-3: Comprehensive User Guide Table of Contents 1. Product Overview 2. Key Applications 3. Usage Instructions 4. Detailed Use Cases 5. Contact Information 1. Product Overview Product Name: N-(2-chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine CAS Number: 444731-75-3 Molecular Formula: C\u2081\u2084H\u2081\u2085ClN\u2086 Molecular Weight: 302.76 g\/mol Appearance: White to off-white crystalline powder Purity: \u226598% (HPLC) Storage: Store at 2-8\u00b0C in [&hellip;]<\/p>","protected":false},"featured_media":21253,"comment_status":"closed","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[15],"product_tag":[],"class_list":{"0":"post-165","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-uncategorized","8":"first","9":"instock","10":"product-type-simple"},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v24.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Factory Supply N-(2-chloropyriMidin-4-yl)-N,2,3-triMethyl-2H-indazol-6-aMine CAS 444731-75-3 With Best Price - Welcome to VIVALR- Your Trusted Source for Chemical Raw Materials\uff01<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/vivalr.com\/en_au\/product\/165.html\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Factory Supply N-(2-chloropyriMidin-4-yl)-N,2,3-triMethyl-2H-indazol-6-aMine CAS 444731-75-3 With Best Price\" \/>\n<meta property=\"og:description\" content=\"N-(2-chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine CAS 444731-75-3: Comprehensive User Guide Table of Contents 1. 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Product Overview Product Name: N-(2-chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine CAS Number: 444731-75-3 Molecular Formula: C\u2081\u2084H\u2081\u2085ClN\u2086 Molecular Weight: 302.76 g\/mol Appearance: White to off-white crystalline powder Purity: \u226598% (HPLC) Storage: Store at 2-8\u00b0C in [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/vivalr.com\/en_au\/product\/165.html\" \/>\n<meta property=\"og:site_name\" content=\"Welcome to VIVALR- Your Trusted Source for Chemical Raw Materials\uff01\" \/>\n<meta property=\"article:modified_time\" content=\"2025-03-07T12:21:34+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/vivalr.com\/wp-content\/uploads\/2025\/03\/N-2-chloropyriMidin-4-yl-N23-triMethyl-2H-indazol-6-aMine-CAS-444731-75-3.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"350\" \/>\n\t<meta property=\"og:image:height\" content=\"350\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/vivalr.com\\\/product\\\/165.html\",\"url\":\"https:\\\/\\\/vivalr.com\\\/product\\\/165.html\",\"name\":\"Factory Supply N-(2-chloropyriMidin-4-yl)-N,2,3-triMethyl-2H-indazol-6-aMine CAS 444731-75-3 With Best Price - Welcome to VIVALR- Your Trusted Source for Chemical Raw Materials\uff01\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/vivalr.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/vivalr.com\\\/product\\\/165.html#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/vivalr.com\\\/product\\\/165.html#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/vivalr.com\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/N-2-chloropyriMidin-4-yl-N23-triMethyl-2H-indazol-6-aMine-CAS-444731-75-3.jpg\",\"datePublished\":\"2025-03-07T12:05:11+00:00\",\"dateModified\":\"2025-03-07T12:21:34+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/vivalr.com\\\/product\\\/165.html#breadcrumb\"},\"inLanguage\":\"en-AU\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/vivalr.com\\\/product\\\/165.html\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-AU\",\"@id\":\"https:\\\/\\\/vivalr.com\\\/product\\\/165.html#primaryimage\",\"url\":\"https:\\\/\\\/vivalr.com\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/N-2-chloropyriMidin-4-yl-N23-triMethyl-2H-indazol-6-aMine-CAS-444731-75-3.jpg\",\"contentUrl\":\"https:\\\/\\\/vivalr.com\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/N-2-chloropyriMidin-4-yl-N23-triMethyl-2H-indazol-6-aMine-CAS-444731-75-3.jpg\",\"width\":350,\"height\":350},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/vivalr.com\\\/product\\\/165.html#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/vivalr.com\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Shop\",\"item\":\"https:\\\/\\\/vivalr.com\\\/shop\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Factory Supply N-(2-chloropyriMidin-4-yl)-N,2,3-triMethyl-2H-indazol-6-aMine CAS 444731-75-3 With Best Price\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/vivalr.com\\\/#website\",\"url\":\"https:\\\/\\\/vivalr.com\\\/\",\"name\":\"Welcome to VIVALR- Your Trusted Source for Chemical Raw Materials\uff01\",\"description\":\"Discover a wide range of high-quality chemical raw materials to meet your industrial needs. 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