{"id":1725,"date":"2025-03-07T12:06:51","date_gmt":"2025-03-07T12:06:51","guid":{"rendered":"https:\/\/vivalr.com\/product\/1725.html"},"modified":"2025-03-07T12:25:04","modified_gmt":"2025-03-07T12:25:04","slug":"factory-supply-44%e2%80%b2-dimethoxytrityl-chloride-cas-40615-36-9-with-low-price","status":"publish","type":"product","link":"https:\/\/vivalr.com\/en_au\/product\/1725.html","title":{"rendered":"Factory Supply 4,4\u2032-Dimethoxytrityl chloride CAS 40615-36-9 With Low Price"},"content":{"rendered":"<div class=\"user-guide\">\n<h1>4,4\u2032-Dimethoxytrityl Chloride CAS 40615-36-9: Factory Supply with Competitive Pricing<\/h1>\n<p>        <!-- Table of Contents --><\/p>\n<div class=\"toc\">\n<h2>Table of Contents<\/h2>\n<ul>\n<li><a href=\"#product-info\">1. Product Information<\/a><\/li>\n<li><a href=\"#applications\">2. Applications<\/a><\/li>\n<li><a href=\"#usage-instructions\">3. Usage Instructions<\/a><\/li>\n<li><a href=\"#case-studies\">4. Case Studies<\/a><\/li>\n<li><a href=\"#contact\">5. Contact<\/a><\/li>\n<\/ul><\/div>\n<p>        <!-- Product Information --><\/p>\n<section id=\"product-info\">\n<h2>1. Product Information<\/h2>\n<p><strong>4,4\u2032-Dimethoxytrityl Chloride (DMT-Cl)<\/strong> is a high-purity chemical reagent widely used in oligonucleotide synthesis. Key specifications include:<\/p>\n<ul>\n<li><strong>CAS Number:<\/strong> 40615-36-9<\/li>\n<li><strong>Molecular Formula:<\/strong> C<sub>21<\/sub>H<sub>19<\/sub>ClO<sub>2<\/sub><\/li>\n<li><strong>Molecular Weight:<\/strong> 338.83 g\/mol<\/li>\n<li><strong>Appearance:<\/strong> White to off-white crystalline powder<\/li>\n<li><strong>Purity:<\/strong> \u226598% (HPLC)<\/li>\n<li><strong>Storage:<\/strong> 2-8\u00b0C, protected from light and moisture<\/li>\n<li><strong>Packaging:<\/strong> Available in 1kg, 5kg, and custom quantities.<\/li>\n<\/ul>\n<\/section>\n<p>        <!-- Applications --><\/p>\n<section id=\"applications\">\n<h2>2. Applications<\/h2>\n<p>4,4\u2032-Dimethoxytrityl Chloride is essential in:<\/p>\n<ul>\n<li><strong>Oligonucleotide Synthesis:<\/strong> Acts as a protecting group for 5\u2032-hydroxyl groups in DNA\/RNA synthesis.<\/li>\n<li><strong>Solid-Phase Synthesis:<\/strong> Prevents unwanted side reactions during nucleotide coupling.<\/li>\n<li><strong>Research & Pharmaceuticals:<\/strong> Used in antisense oligonucleotides, siRNA, and diagnostic probes.<\/li>\n<\/ul>\n<\/section>\n<p>        <!-- Usage Instructions --><\/p>\n<section id=\"usage-instructions\">\n<h2>3. Usage Instructions<\/h2>\n<h3>Step-by-Step Guide:<\/h3>\n<ol>\n<li><strong>Preparation:<\/strong> Work under anhydrous conditions in an inert atmosphere (e.g., argon).<\/li>\n<li><strong>Dissolution:<\/strong> Dissolve DMT-Cl in anhydrous acetonitrile or dichloromethane (0.1-0.3M).<\/li>\n<li><strong>Reaction:<\/strong> Add the solution to the nucleoside\/resin at room temperature for 15-30 minutes.<\/li>\n<li><strong>Quenching:<\/strong> Terminate the reaction with methanol or ethanol.<\/li>\n<li><strong>Purification:<\/strong> Use silica gel chromatography or filtration for isolation.<\/li>\n<\/ol>\n<p><em>Note:<\/em> Avoid prolonged exposure to moisture or acidic conditions.<\/p>\n<\/section>\n<p>        <!-- Case Studies --><\/p>\n<section id=\"case-studies\">\n<h2>4. Case Studies<\/h2>\n<h3>Case 1: DNA Oligomer Synthesis<\/h3>\n<p>A research team synthesized a 20-mer DNA strand using DMT-Cl as the 5\u2032-protecting group. The tritylation efficiency reached 95%, confirmed by HPLC. Post-synthesis, the DMT group was removed with 3% dichloroacetic acid, yielding high-purity product.<\/p>\n<h3>Case 2: RNA Probe Development<\/h3>\n<p>In an siRNA project, DMT-Cl ensured selective protection during solid-phase synthesis. The process achieved 90% coupling efficiency under RNase-free conditions, critical for functional RNA probes.<\/p>\n<h3>Case 3: Modified Nucleotide Production<\/h3>\n<p>A pharmaceutical company utilized DMT-Cl to produce fluorescently labeled nucleotides for diagnostic assays. The product demonstrated stability across pH 6-8, validated by mass spectrometry.<\/p>\n<\/section>\n<p>        <!-- Contact --><\/p>\n<section id=\"contact\">\n<h2>5. Contact<\/h2>\n<address>\n                For inquiries or orders, contact:<br \/>\n                Email: <a href=\"mailto:info@vivalr.com\">info@vivalr.com<\/a><br \/>\n                Phone: <a href=\"tel:+8615866781826\">(86) 15866781826<\/a><br \/>\n            <\/address>\n<\/section><\/div>","protected":false},"excerpt":{"rendered":"<p>4,4\u2032-Dimethoxytrityl Chloride CAS 40615-36-9: Factory Supply with Competitive Pricing Table of Contents 1. Product Information 2. Applications 3. Usage Instructions 4. Case Studies 5. Contact 1. Product Information 4,4\u2032-Dimethoxytrityl Chloride (DMT-Cl) is a high-purity chemical reagent widely used in oligonucleotide synthesis. Key specifications include: CAS Number: 40615-36-9 Molecular Formula: C21H19ClO2 Molecular Weight: 338.83 g\/mol Appearance: [&hellip;]<\/p>\n","protected":false},"featured_media":22018,"comment_status":"closed","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[15],"product_tag":[],"class_list":{"0":"post-1725","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-uncategorized","8":"first","9":"instock","10":"product-type-simple"},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v24.4 (Yoast SEO v28.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Factory Supply 4,4\u2032-Dimethoxytrityl chloride CAS 40615-36-9 With Low Price - Welcome to VIVALR- Your Trusted Source for Chemical Raw Materials\uff01<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/vivalr.com\/en_au\/product\/1725.html\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Factory Supply 4,4\u2032-Dimethoxytrityl chloride CAS 40615-36-9 With Low Price\" \/>\n<meta property=\"og:description\" content=\"4,4\u2032-Dimethoxytrityl Chloride CAS 40615-36-9: Factory Supply with Competitive Pricing Table of Contents 1. Product Information 2. Applications 3. Usage Instructions 4. Case Studies 5. Contact 1. Product Information 4,4\u2032-Dimethoxytrityl Chloride (DMT-Cl) is a high-purity chemical reagent widely used in oligonucleotide synthesis. 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Product Information 2. Applications 3. Usage Instructions 4. Case Studies 5. Contact 1. Product Information 4,4\u2032-Dimethoxytrityl Chloride (DMT-Cl) is a high-purity chemical reagent widely used in oligonucleotide synthesis. 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