3-iodophenol, with the CAS number 626-02-8, is an important organic compound. It is a white to light yellow crystalline powder. The molecular formula of 3-iodophenol is C₆H₅IO, and its molecular weight is approximately 220.01 g/mol. The melting point of this compound ranges from 42 - 45°C, and it has relatively low solubility in water but is soluble in organic solvents such as ethanol, ether, and chloroform.
Our factory provides high - quality 3-iodophenol with a purity that typically exceeds 98%. We ensure strict quality control during the production process, and the product is packed in sealed containers to prevent oxidation and contamination.
3-iodophenol has a wide range of applications in the chemical and pharmaceutical industries.
In the field of organic synthesis, it serves as a key intermediate. It can be used to synthesize various complex organic compounds, including pharmaceuticals, pesticides, and dyes. For example, it can participate in coupling reactions to form new carbon - carbon or carbon - heteroatom bonds, which are crucial steps in the construction of many bioactive molecules.
In the pharmaceutical industry, 3-iodophenol is used in the synthesis of drugs with antibacterial, anti - inflammatory, and analgesic properties. Some research also suggests that derivatives of 3-iodophenol may have potential applications in the treatment of certain cancers and neurological diseases.
When using 3-iodophenol, proper safety precautions should be taken. It is recommended to wear appropriate personal protective equipment, such as gloves, goggles, and a lab coat. The compound should be handled in a well - ventilated area or under a fume hood to avoid inhalation of dust or vapors.
For laboratory use, accurate weighing of 3-iodophenol is essential. Use a calibrated balance to measure the desired amount. When dissolving it in an organic solvent, add the solvent slowly while stirring to ensure complete dissolution. In chemical reactions, follow the reaction conditions carefully, including temperature, reaction time, and the addition of catalysts or other reagents.
Caso 1: Síntesis de un intermediario farmacéutico
In a research project for developing a new antibacterial drug, 3-iodophenol was used as a starting material. First, 3-iodophenol was dissolved in anhydrous tetrahydrofuran (THF) under a nitrogen atmosphere. Then, a specific metal catalyst and a coupling reagent were added. The reaction mixture was heated to a certain temperature and stirred for several hours. After the reaction was completed, the product was purified by column chromatography. The resulting intermediate had high biological activity and was further used in the subsequent steps of drug synthesis.
Case 2: Preparation of a Special Dye
A dye manufacturer used 3-iodophenol to synthesize a new type of dye. 3-iodophenol was reacted with a specific aromatic amine in the presence of an acid catalyst. The reaction was carried out in a reflux apparatus at an elevated temperature. The resulting compound had unique light - absorbing properties and was used to dye fabrics, plastics, and other materials, providing them with bright and long - lasting colors.
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