High Quality 3-HYDROXY-2,4,6-TRIIODOBENZOIC ACID CAS 53279-72-4: User Guide

1. Información sobre el producto

3-HYDROXY-2,4,6-TRIIODOBENZOIC ACID (CAS 53279-72-4) is a high-purity iodinated aromatic compound widely used in pharmaceutical and chemical research. Key specifications include:

• Fórmula química: C₇H₃I₃O₃
• Peso molecular: 499.81 g/mol
• Apariencia: Polvo cristalino entre blanquecino y amarillo pálido
• Pureza: ≥98% (HPLC)
• Solubilidad: Soluble in alkaline solutions, DMSO, and DMF
• Almacenamiento: Conservar en lugar fresco, seco y protegido de la luz a 2-8°C

2. Uso del producto

Este compuesto desempeña funciones críticas en:

• X-ray Contrast Media: Intermediate for iodinated contrast agents in medical imaging.
• Síntesis orgánica: Building block for pharmaceuticals and specialty chemicals.
• Research Applications: Used in studying iodine-containing compounds’ biochemical behavior.

3. Aplicación del producto

Handling Guidelines:

• Utilizar EPI (guantes, gafas, bata de laboratorio) para evitar el contacto directo.
• Dissolve in alkaline buffers (pH 8-10) for optimal solubility.
• Use under fume hood for large-scale reactions.

Storage Tips: Keep container tightly sealed under inert gas (argon/nitrogen) to prevent degradation.

4. Casos de uso detallados

Case 1: X-ray Contrast Agent Synthesis

Used as a precursor in synthesizing iopamidol, a non-ionic contrast agent for CT scans. Reaction steps involve iodination and hydroxyl group protection, achieving >90% yield under controlled conditions.

Case 2: Antithyroid Drug Intermediate

Key intermediate in producing methimazole analogs. Reacts with thiourea derivatives to form thioamide bonds, enabling iodine-controlled release mechanisms.

Case 3: Radiolabeling Studies

Employed in ¹²⁵I radiolabeling experiments for tracking drug metabolism in preclinical models, with 85% radiochemical purity post-purification.

5. 5. Información de contacto

Para consultas técnicas o pedidos al por mayor:

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