1. Información sobre el producto

3-Isobutyl-1-Methylxanthine (CAS 28822-58-4) is a high-purity xanthine derivative widely used in biochemical and pharmaceutical research. Key specifications include:

• Número CAS: 28822-58-4
• Fórmula molecular: C₉H₁₄N₄O₂
• Peso molecular: 210.23 g/mol
• Apariencia: Polvo cristalino entre blanco y blanquecino
• Pureza: ≥98% (HPLC)
• Almacenamiento: Conservar a 2-8°C en un lugar seco y oscuro

2. Usos del producto

3-Isobutyl-1-Methylxanthine is primarily utilized in:

• Phosphodiesterase (PDE) Inhibition: Acts as a non-selective PDE inhibitor to elevate intracellular cAMP levels.
• Cell Culture Studies: Enhances differentiation in stem cell and adipocyte research.
• Drug Development: Used in studies targeting asthma, inflammation, and neurological disorders.
• In Vitro Diagnostics: Supports enzyme activity assays and signal transduction pathway analysis.

3. Cómo utilizar

• Solubilidad: Soluble in DMSO (50 mg/mL) and ethanol; slightly soluble in water.
• Dosificación: Typical working concentrations range from 0.1-1.0 mM (optimize per experimental conditions).
• Seguridad: Wear PPE (gloves, lab coat, goggles) and work in a well-ventilated area.
• Almacenamiento: Keep sealed in original packaging to avoid moisture and light exposure.

4. Casos prácticos de aplicación

Case Study 1: Adipocyte Differentiation

Researchers used 0.5 mM 3-Isobutyl-1-Methylxanthine in combination with insulin and dexamethasone to induce preadipocyte differentiation into mature adipocytes over 14 days, achieving 85% differentiation efficiency.

Case Study 2: Neurological Research

In Parkinson's disease models, 0.2 mM of this compound was applied to enhance dopamine receptor signaling, improving therapeutic outcomes in in vitro neuronal cultures.

5. Contacto

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