1. Descripción general del producto

Pexiganan (CAS 147664-63-9) is a synthetic antimicrobial peptide with a molecular formula of C₁₁₉H₁₈₅N₃₅O₂₄ and a molecular weight of approximately 2414.0 g/mol. This white lyophilized powder has a purity of ≥98% (HPLC) and is stored at -20°C to maintain stability. It is designed for research and pharmaceutical development.

2. Applications of Pexiganan

Pexiganan is primarily used as a topical antibacterial agent to treat infections, including diabetic foot ulcers and skin infections caused by Gram-positive and Gram-negative bacteria. Its broad-spectrum activity and low resistance potential make it a promising alternative to traditional antibiotics.

3. Instrucciones de uso

1. Reconstitución: Dissolve in sterile distilled water or saline to achieve a 1-2 mg/mL solution.
2. Aplicación: Apply topically to affected areas twice daily or incorporate into hydrogel dressings.
3. Almacenamiento: Store reconstituted solutions at 2-8°C for up to 7 days.
4. Seguridad: Conduct pH and sterility tests before large-scale use.

4. Casos de uso detallados

Case Study 1: Diabetic Foot Ulcer Treatment

Escenario: A patient with a non-healing ulcer infected by Staphylococcus aureus.

Protocolo: Pexiganan (2 mg/mL gel) was applied twice daily for 14 days. Results showed a 90% reduction in bacterial load and accelerated wound closure.

Case Study 2: Burn Infection Management

Escenario: Second-degree burns with Pseudomonas aeruginosa contamination.

Protocolo: Pexiganan-infused dressings were replaced every 24 hours. Infection clearance was achieved within 7 days, preventing systemic spread.