The product, named High Quality l-10-camphorsulfonic acid with CAS number 35963 - 20 - 3, is a chemical substance known for its high quality and low price. Its molecular formula is C₁₀H₁₆O₄S. It appears as a white to off - white crystalline powder. The melting point of this product is in the range of 195 - 200 °C, and it has a relatively high purity level, usually above 98%.
It is soluble in water, ethanol, and other polar solvents, which provides good solubility for various chemical reactions and applications. The density of l - 10 - camphorsulfonic acid is approximately 1.31 g/cm³. These physical and chemical properties make it a versatile chemical in different industries.
1. **In Organic Synthesis**: l - 10 - camphorsulfonic acid is widely used as a chiral resolving agent in organic synthesis. It can be used to separate racemic mixtures into their enantiomers, which is crucial for the production of pure chiral compounds. For example, in the synthesis of pharmaceuticals, many drug molecules are chiral, and only one enantiomer may have the desired pharmacological activity, while the other may be inactive or even have side - effects. Using l - 10 - camphorsulfonic acid can help in obtaining the pure active enantiomer.
2. **As an Acid Catalyst**: It serves as an acid catalyst in various chemical reactions, such as esterification and acetalization reactions. The acidic nature of l - 10 - camphorsulfonic acid can accelerate these reactions, leading to higher reaction rates and better yields.
3. **In Polymerization**: In some polymerization processes, l - 10 - camphorsulfonic acid can be used as an initiator or a modifier. It can affect the polymerization rate, molecular weight, and other properties of the resulting polymers, making them suitable for different applications, such as in the production of plastics and elastomers.
1. **Handling and Storage**: When handling l - 10 - camphorsulfonic acid, it is necessary to wear appropriate protective equipment, such as gloves and goggles, to prevent contact with skin and eyes. It should be stored in a cool, dry place away from direct sunlight and sources of heat. Keep it in a tightly sealed container to avoid moisture absorption and contamination.
2. **Dosage and Addition in Reactions**: In chemical reactions, the dosage of l - 10 - camphorsulfonic acid should be carefully calculated according to the reaction conditions and the amount of reactants. Usually, it is added in small increments during the reaction process, and the reaction progress should be monitored to ensure optimal results.
3. **Safety Precautions**: Avoid inhalation of dust or mist. In case of accidental contact with skin, wash thoroughly with plenty of water. If it gets into the eyes, rinse immediately with water and seek medical attention. In case of ingestion, do not induce vomiting and seek medical help immediately.
1. **Pharmaceutical Industry**: A pharmaceutical company was synthesizing a new chiral drug. They used l - 10 - camphorsulfonic acid as a chiral resolving agent. By dissolving the racemic mixture in a suitable solvent and adding l - 10 - camphorsulfonic acid, they were able to form diastereomeric salts. After crystallization and separation, they obtained the pure enantiomer of the drug with a high yield of over 80%. This pure enantiomer showed excellent pharmacological activity in subsequent animal experiments and clinical trials, and it was successfully developed into a new drug.
2. **Polymer Industry**: A polymer manufacturing company was producing a special type of polyester. They added l - 10 - camphorsulfonic acid as a catalyst during the esterification reaction. The use of l - 10 - camphorsulfonic acid significantly increased the reaction rate, reducing the reaction time from several hours to less than an hour. The resulting polyester had better mechanical properties and thermal stability, which made it suitable for use in high - performance engineering plastics.
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