Sodium Trichloroacetate with the CAS number 650 - 51 - 1 is a chemical compound offered by factory supply at the best price. The chemical formula of Sodium Trichloroacetate is C₂Cl₃NaO₂. It appears as a white to off - white crystalline powder. The molecular weight of this compound is approximately 195.37 g/mol. It has good solubility in water, which makes it suitable for various aqueous - based applications. The melting point of Sodium Trichloroacetate is typically around 190 - 195 °C, and it should be stored in a cool, dry place away from strong oxidizing agents and acids to maintain its chemical stability.
Sodium Trichloroacetate has a wide range of applications in different industries. In the pharmaceutical industry, it can be used as an intermediate in the synthesis of certain drugs. Its unique chemical structure allows it to participate in specific chemical reactions that are crucial for the production of active pharmaceutical ingredients. For example, it can be involved in esterification and substitution reactions to form more complex chemical compounds used in drug formulations.
In the field of organic synthesis, Sodium Trichloroacetate serves as a valuable reagent. It can be used to introduce trichloroacetyl groups into organic molecules, which can significantly change the physical and chemical properties of the target compounds. This property is often utilized in the synthesis of specialty chemicals and fine - chemicals.
It also finds applications in the research laboratory. Scientists use it for exploring new chemical reactions and developing novel synthetic routes. Due to its relatively stable chemical nature under certain conditions, it provides a reliable starting material for various experimental studies.
When using Sodium Trichloroacetate, proper safety precautions should be taken. Always wear appropriate personal protective equipment, such as gloves, goggles, and a lab coat. First, measure the required amount of Sodium Trichloroacetate accurately using a balance. If it is to be used in an aqueous solution, dissolve it slowly in water under gentle stirring. The rate of dissolution can be affected by the temperature of the water. Generally, using slightly warm water can speed up the dissolution process, but avoid using overly hot water as it may cause decomposition of the compound.
When using it in chemical reactions, follow the reaction conditions strictly. Control the reaction temperature, pressure, and reaction time according to the specific reaction requirements. It is often recommended to carry out reactions in a well - ventilated fume hood to prevent the inhalation of any potentially harmful vapors.
Caso práctico 1: Síntesis farmacéutica
A pharmaceutical company was synthesizing a new anti - inflammatory drug. Sodium Trichloroacetate was used as an intermediate. The research team first dissolved Sodium Trichloroacetate in an appropriate organic solvent. Then, through a series of carefully controlled substitution and cyclization reactions, they were able to introduce the necessary functional groups into the molecular structure of the drug precursor. By optimizing the reaction conditions, such as adjusting the reaction temperature and the ratio of reactants, they achieved a high yield of the desired intermediate. This intermediate was then further processed to obtain the final anti - inflammatory drug, which showed excellent efficacy in pre - clinical trials.
Case Study 2: Organic Synthesis in a Research Lab
A research group in a university was exploring a new synthetic method for a class of fluorescent compounds. They used Sodium Trichloroacetate to introduce a trichloroacetyl group into a simple aromatic compound. By carefully controlling the reaction conditions, they were able to obtain a new compound with enhanced fluorescent properties. This discovery not only provided a new way for the synthesis of fluorescent materials but also deepened the understanding of the chemical reactivity of Sodium Trichloroacetate.
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