The product, (S)-(-)-2,2′-Bis(diphenylphosphino)-1,1′-binaphthyl with the CAS number 76189-56-5, is a high - quality chemical compound supplied directly from the factory at the best price. This chiral diphosphine ligand is well - known in the field of organic chemistry. Its chemical formula is C44H32P2, and it has a molecular weight of approximately 622.67 g/mol. It usually appears as a white to off - white powder. The product shows good stability under normal storage conditions, but it should be kept away from strong oxidizing agents, moisture, and direct sunlight. It is soluble in common organic solvents such as toluene, dichloromethane, and tetrahydrofuran.
(S)-(-)-2,2′-Bis(diphenylphosphino)-1,1′-binaphthyl serves as a crucial chiral ligand in asymmetric catalysis. Asymmetric catalysis is of great significance in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals. This ligand can be used in a variety of catalytic reactions, including hydrogenation, hydroformylation, and cross - coupling reactions. In the synthesis of chiral drugs, it can help to control the stereochemistry of the reaction, leading to the formation of enantiomerically pure products. For example, in the preparation of anti - inflammatory drugs, the use of this ligand can improve the efficiency and selectivity of the synthesis process, resulting in better - quality products with fewer side - effects.
When using (S)-(-)-2,2′-Bis(diphenylphosphino)-1,1′-binaphthyl, it is essential to follow proper laboratory procedures. First, ensure that you are working in a well - ventilated area. Wear appropriate personal protective equipment, such as gloves and safety glasses. Before use, check the appearance of the product. If it shows signs of discoloration or agglomeration, it may have been damaged during storage. Weigh the required amount of the product accurately using a balance in a dry environment. When adding it to the reaction system, use a dry syringe or spatula to avoid introducing moisture. In the reaction process, control the temperature, pressure, and reaction time according to the specific reaction conditions. After the reaction, the product can be separated and purified by common methods such as column chromatography or recrystallization.
Case 1: In a pharmaceutical company, they were synthesizing a chiral anti - cancer drug. By using (S)-(-)-2,2′-Bis(diphenylphosphino)-1,1′-binaphthyl as a ligand in a palladium - catalyzed cross - coupling reaction, they were able to achieve a high enantiomeric excess (ee) of over 95%. The reaction conditions were optimized by adjusting the ratio of the ligand to the palladium catalyst and the reaction temperature. The yield of the desired product was significantly improved compared to previous methods without using this chiral ligand.
Case 2: An agrochemical research institute was developing a new type of chiral insecticide. They employed this ligand in a rhodium - catalyzed hydrogenation reaction. The use of (S)-(-)-2,2′-Bis(diphenylphosphino)-1,1′-binaphthyl led to a more efficient reaction process with reduced reaction time. The resulting chiral insecticide showed enhanced biological activity and selectivity against target pests, making it a more effective and environmentally friendly product.
If you have any questions or needs regarding (S)-(-)-2,2′-Bis(diphenylphosphino)-1,1′-binaphthyl, please feel free to contact us. Our email address is info@vivalr.com, and our phone number is (86) 15866781826. We will provide you with professional technical support and high - quality products.
Este es William, CEO de Zhishang Chemical Co., Ltd.
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