The product we are introducing is High Quality 1,1 - Cyclobutanedicarboxylic acid with CAS number 5445 - 51 - 2 and is available at a low price. The molecular formula of 1,1 - Cyclobutanedicarboxylic acid is C₆H₈O₄, and its molecular weight is approximately 144.12 g/mol. It appears as a white to off - white crystalline powder. This compound has a melting point range, typically around 170 - 175 °C. It has relatively good stability under normal storage conditions but should be kept away from strong oxidizing agents and extreme temperatures.
1,1 - Cyclobutanedicarboxylic acid has a wide range of applications in the chemical and pharmaceutical industries. In the pharmaceutical field, it serves as an important intermediate for the synthesis of various drugs. Due to its unique cyclobutane structure, it can be used to modify the pharmacokinetic properties of drugs, such as improving solubility and bioavailability. For example, it can be incorporated into drug molecules to enhance their binding affinity to specific receptors, leading to more effective therapeutic outcomes.
In the chemical industry, it is used in the production of high - performance polymers. The carboxylic acid groups on the molecule can participate in polymerization reactions, forming polymers with excellent mechanical and thermal properties. These polymers can be used in applications such as engineering plastics, coatings, and adhesives.
When using 1,1 - Cyclobutanedicarboxylic acid, appropriate safety precautions should be taken. Wear suitable protective clothing, gloves, and eye/face protection. It is advisable to work in a well - ventilated area to avoid inhalation of dust. When handling the product, use clean and dry tools to prevent contamination.
In a laboratory setting, for synthesis reactions, the amount of 1,1 - Cyclobutanedicarboxylic acid used should be accurately measured according to the reaction stoichiometry. It can be dissolved in common organic solvents such as ethanol, methanol, or dimethylformamide (DMF) depending on the reaction requirements. The reaction conditions, including temperature, reaction time, and catalyst, should be strictly controlled to ensure the desired reaction outcome.
Caso 1: Síntesis farmacéutica
A research team was working on developing a new antihypertensive drug. They used 1,1 - Cyclobutanedicarboxylic acid as an intermediate in the synthesis process. By reacting it with a specific amine compound under carefully controlled conditions, they were able to introduce the cyclobutane moiety into the drug molecule. This modification improved the drug's solubility in water, which in turn enhanced its absorption in the body. In pre - clinical trials, the new drug showed better efficacy in reducing blood pressure compared to the existing drugs in the market, with fewer side effects.
Caso 2: Producción de polímeros
A chemical company was aiming to develop a new type of engineering plastic with high heat resistance. They incorporated 1,1 - Cyclobutanedicarboxylic acid into the polymerization reaction of a polyester resin. The resulting polymer had a higher glass transition temperature (Tg) and better mechanical strength compared to the traditional polyester plastics. The new engineering plastic was successfully used in the manufacturing of automotive parts that required high - temperature resistance, such as engine covers and radiator grilles.
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Este es William, CEO de Zhishang Chemical Co., Ltd.
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