Polyglyceryl-2 Triisostearate with the CAS number 120486-24-0 is a high - quality product offered at the best price. It is a non - ionic surfactant and emollient. Chemically, it is a complex ester formed by the reaction of polyglyceryl - 2 and triisostearic acid.
The product typically appears as a pale yellow to amber liquid. It has a specific gravity in the range of approximately 0.92 - 0.96 g/cm³ at 25°C. The acid value is usually less than 5 mg KOH/g, and the saponification value ranges from 130 - 160 mg KOH/g. Its HLB (Hydrophilic - Lipophilic Balance) value is around 3 - 5, indicating its lipophilic nature, which makes it suitable for use in oil - based formulations.
1. Cosmetics Industry: In cosmetics, Polyglyceryl - 2 Triisostearate is widely used as an emulsifier. It helps to create stable oil - in - water or water - in - oil emulsions. For example, in moisturizing creams and lotions, it can keep the oil and water phases from separating, providing a smooth and uniform texture. It is also used in hair care products such as hair conditioners. It helps to reduce the surface tension between the hair strands, making the hair softer, smoother, and more manageable.
2. Pharmaceutical Industry: In pharmaceutical formulations, it can be used as a solubilizer and carrier for lipophilic drugs. It can improve the solubility and bioavailability of certain drugs, especially those with poor water solubility. Additionally, it can be used in topical pharmaceutical preparations to enhance the spreadability and moisturizing effect of the formulation.
1. For Emulsion Preparation: When using Polyglyceryl - 2 Triisostearate in an emulsion, first heat the oil phase and the water phase separately to around 70 - 80°C. Then, slowly add the oil phase to the water phase while stirring vigorously. Add the appropriate amount of Polyglyceryl - 2 Triisostearate to the oil phase before mixing. The recommended dosage is usually in the range of 1 - 5% depending on the specific formulation requirements. After mixing, continue to stir until the emulsion cools down to room temperature.
2. In Hair Care Products: In hair conditioners, it can be directly added to the formulation during the manufacturing process. The typical dosage is about 0.5 - 2%. After adding, ensure thorough mixing to achieve a homogeneous product.
1. Cosmetic Company A: This company was developing a new line of anti - aging moisturizing creams. They used Polyglyceryl - 2 Triisostearate as the main emulsifier. By using a 3% dosage of this product, they were able to create a stable oil - in - water emulsion. The cream had a smooth texture and did not separate even after being stored at different temperatures for several months. Consumers reported that the cream was easy to apply and provided long - lasting moisturization.
2. Pharmaceutical Company B: Company B was working on a topical antifungal cream. They used Polyglyceryl - 2 Triisostearate as a solubilizer for the lipophilic antifungal drug. By incorporating 2% of the product into the formulation, they significantly improved the drug's solubility and bioavailability. Clinical trials showed that the new formulation was more effective in treating fungal infections compared to the previous formulation without this ingredient.
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