Choline dihydrogencitrate salt, identified by the CAS number 77 - 91 - 8, is a high - quality compound available at the best price. It is a white crystalline powder with high solubility in water. This compound is known for its high purity, which is typically above 99%. The melting point of Choline dihydrogencitrate salt ranges from 150 - 155°C. It has a molecular formula of C₁₁H₂₁NO₇ and a molecular weight of approximately 279.29 g/mol.
1. **Nutritional Supplements**: Choline is an essential nutrient for humans. Choline dihydrogencitrate salt is widely used in the production of nutritional supplements. It plays a crucial role in brain health, supporting cognitive function and memory. It is also involved in liver function, helping to prevent the accumulation of fat in the liver and maintaining normal liver metabolism.
2. **Animal Feed**: In the animal husbandry industry, it is added to animal feed. It promotes the growth and development of animals, improves their immunity, and enhances the quality of animal products such as meat, eggs, and milk.
3. **Pharmaceutical Industry**: It can be used as an intermediate in the synthesis of some pharmaceutical products. Its properties make it a valuable ingredient in the development of drugs targeting neurological and metabolic disorders.
1. **For Nutritional Supplements**: When using it in the production of nutritional supplements, the recommended dosage varies depending on the age, gender, and health status of the target population. For adults, the daily intake can range from 500 - 1000 mg. It can be formulated into tablets, capsules, or liquid solutions. The product should be stored in a cool, dry place away from direct sunlight.
2. **In Animal Feed**: The amount added to animal feed depends on the type of animal and its growth stage. For poultry, it can be added at a rate of 0.1 - 0.3% of the total feed weight. For pigs, the addition rate can be around 0.15 - 0.35%. It should be evenly mixed with other feed ingredients to ensure uniform distribution.
3. **In the Pharmaceutical Industry**: Pharmaceutical manufacturers should follow strict quality control procedures. The product should be handled in a cleanroom environment to avoid contamination. The dosage and formulation are determined based on the specific requirements of the drug being developed.
1. **Human Nutritional Supplement Case**: A group of middle - aged adults with mild cognitive impairment took a nutritional supplement containing Choline dihydrogencitrate salt for 6 months. After the study period, cognitive function tests showed significant improvement in memory, attention, and information processing speed compared to the control group. The participants reported feeling more mentally alert and focused in their daily lives.
2. **Poultry Feed Case**: A poultry farm added Choline dihydrogencitrate salt to the feed of 500 broiler chickens. The chickens showed a 10% increase in weight gain compared to the control group. The mortality rate also decreased by 5%, and the quality of the chicken meat was improved, with higher protein content and better texture.
3. **Pharmaceutical Development Case**: A pharmaceutical company used Choline dihydrogencitrate salt as an intermediate in the development of a new drug for Alzheimer's disease. During the pre - clinical trials, the drug showed promising results in reducing the accumulation of amyloid - beta plaques in the brains of animal models, which is a key pathological feature of Alzheimer's disease.
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