Guanosine is a nucleoside that consists of guanine and ribose. Its CAS number is 118 - 00 - 3. Guanosine has a molecular formula of C₁₀H₁₃N₅O₅ and a molecular weight of approximately 283.24 g/mol. It appears as a white to off - white crystalline powder. The melting point of Guanosine is around 230 - 240 °C (decomposition). It is sparingly soluble in water and soluble in dilute acids and alkalis. This Factory Supply Guanosine is provided at a good price, ensuring high - quality raw material for various applications.
1. **Biochemical Research**: Guanosine plays a crucial role in biochemical research. It is involved in many cellular processes, such as signal transduction pathways. In studies related to nucleotide metabolism and gene expression, Guanosine is used as a key reagent to understand the fundamental biological mechanisms.
2. **Pharmaceutical Industry**: It can be used as an intermediate in the synthesis of some drugs. For example, it may be involved in the production of antiviral drugs, as guanine - based compounds often have antiviral properties. Some drugs target the viral replication process by interfering with the guanosine - related metabolic pathways in the virus.
3. **Nutritional Supplements**: Guanosine has potential health benefits. It may contribute to the normal functioning of the nervous system. Some nutritional supplement formulations include Guanosine to support cognitive function and overall brain health.
1. **In Biochemical Experiments**: When using Guanosine in biochemical research, it is usually prepared as a stock solution. First, weigh an appropriate amount of Guanosine according to the experimental protocol. Then, dissolve it in a suitable solvent, such as a buffer solution with a specific pH. The concentration of the stock solution should be carefully calculated based on the subsequent experimental requirements. After preparation, the solution should be stored at an appropriate temperature, usually at 4 °C or - 20 °C, to maintain its stability.
2. **In Pharmaceutical Synthesis**: In the pharmaceutical industry, Guanosine is used as a starting material or intermediate. The reaction conditions, such as temperature, pressure, and the presence of catalysts, need to be strictly controlled according to the specific synthetic route. Chemical reactions may involve multiple steps, and purification processes are required after each reaction step to obtain the pure product.
3. **As a Nutritional Supplement**: If Guanosine is used as a nutritional supplement, it should be taken according to the recommended dosage. It is advisable to consult a healthcare professional before starting to take any new supplement. The supplement can be taken orally with water, preferably with a meal to improve absorption.
1. **Biochemical Research Case**: A research team was studying the nucleotide metabolism in cancer cells. They used Guanosine as a tracer to track the metabolic pathway of guanine nucleotides. By adding radiolabeled Guanosine to the cell culture medium, they were able to observe how the cancer cells took up and metabolized Guanosine. The results showed that cancer cells had a different metabolic pattern compared to normal cells, which provided valuable insights for the development of new cancer therapies.
2. **Pharmaceutical Synthesis Case**: A pharmaceutical company was developing a new antiviral drug. They used Guanosine as an intermediate in the synthesis process. Through a series of chemical reactions, they modified the structure of Guanosine to obtain a compound with potent antiviral activity. The new drug was tested in pre - clinical and clinical trials, and it showed promising results in treating certain viral infections.
3. **Nutritional Supplement Case**: A group of volunteers with mild cognitive impairment participated in a study on the effects of Guanosine - containing nutritional supplements. After taking the supplement for three months, the volunteers showed significant improvements in cognitive function tests, such as memory and attention. The study suggested that Guanosine may have potential in supporting brain health in people with mild cognitive decline.
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