1. Chemical Information & Specifications

DEPS (N, N-diethyl propargylamine propane) is a specialized organic compound with CAS number 70155-90-7. Key specifications include:

• Fórmula molecular: C8H15N
• Peso molecular: 125.21 g/mol
• Apariencia: Líquido claro, incoloro a amarillo pálido
• Pureza: ≥98% (análisis GC)
• Almacenamiento: Store at 2-8°C in a tightly sealed container, away from light and moisture.

2. Key Applications & Uses

DEPS is widely utilized in:

• Intermedios farmacéuticos: Síntesis de moléculas bioactivas y candidatos a fármacos.
• Síntesis orgánica: Acts as a propargylating agent in cross-coupling reactions.
• Productos agroquímicos: Building block for herbicides and fungicides.
• Investigación y desarrollo: Key reagent in organometallic chemistry studies.

3. Safe Handling & Usage Guidelines

• Ventilación: Use in a well-ventilated fume hood to avoid vapor inhalation.
• Protective Equipment: Wear nitrile gloves, safety goggles, and lab coats.
• Manipulación: Avoid contact with oxidizing agents; keep away from heat/sparks.
• Almacenamiento: Use amber glass bottles under inert gas (N2/Ar) for long-term stability.

4. Casos prácticos

Caso práctico 1: Síntesis de intermedios farmacéuticos

DEPS was employed as a propargylamine donor in a palladium-catalyzed Sonogashira reaction to synthesize a tyrosine kinase inhibitor precursor. The reaction achieved 92% yield under mild conditions (room temperature, 12 hours).

Estudio de caso 2: Desarrollo agroquímico

Researchers used DEPS to prepare a novel fungicidal compound via copper-mediated cyclization. The final product demonstrated 85% efficacy against Botrytis cinerea in lab trials.