The product we are discussing is Cholesterol with CAS number 57 - 88 - 5. Cholesterol is a waxy, fat - like substance that is found in all cells of the body. It has the molecular formula C₂₇H₄₆O and a molar mass of approximately 386.65 g/mol. Cholesterol is insoluble in water but soluble in organic solvents such as ethanol, chloroform, and ether. It is a white or faintly yellowish, crystalline powder with a melting point ranging from 147 - 150 °C. Factory - supplied cholesterol is of high purity, ensuring its reliability for various applications.
1. **Biomedical Research**: Cholesterol plays a crucial role in cell membrane structure and function. In biomedical research, it is used to study cell membrane dynamics, lipid rafts, and membrane - related signaling pathways. It is also used as a precursor for the synthesis of steroid hormones, bile acids, and vitamin D.
2. **Pharmaceutical Industry**: Cholesterol is used in the formulation of liposomes, which are lipid - based drug delivery systems. Liposomes can encapsulate drugs, improve their stability, and enhance their targeting ability, thus increasing the efficacy of drug delivery.
3. **Food Industry**: In the food industry, cholesterol can be used in the production of certain dairy products and processed foods to improve texture and mouth - feel. However, due to health concerns related to high cholesterol intake, the use in food is strictly regulated.
1. **Biomedical Research**: When using cholesterol in biomedical research, it is usually dissolved in an appropriate organic solvent such as ethanol. The concentration of the cholesterol solution depends on the specific experimental requirements. For example, in cell culture experiments, cholesterol solutions are often added to the culture medium at a concentration of 1 - 10 μM. Care should be taken to ensure proper sterilization of the cholesterol solution if it is used in cell culture to avoid contamination.
2. **Pharmaceutical Industry**: In the pharmaceutical industry, cholesterol is used in the preparation of liposomes. First, cholesterol is mixed with other lipids such as phosphatidylcholine in an appropriate molar ratio. The mixture is then dissolved in an organic solvent, and the solvent is evaporated to form a lipid film. Next, an aqueous phase containing the drug is added, and the mixture is subjected to sonication or extrusion to form liposomes.
3. **Food Industry**: In the food industry, cholesterol should be added in accordance with relevant regulations. It is usually mixed with other ingredients during the food production process. Precise measurement of the amount of cholesterol added is necessary to ensure product quality and compliance with health standards.
1. **Cancer Drug Delivery**: A pharmaceutical company was developing a new cancer drug. They used cholesterol to prepare liposomes for drug delivery. By encapsulating the anti - cancer drug in cholesterol - based liposomes, they were able to improve the drug's solubility and targeting ability. In in - vitro experiments, the liposomal drug showed higher cytotoxicity to cancer cells compared to the free drug. In in - vivo experiments on mice models, the liposomal drug significantly inhibited tumor growth, demonstrating the effectiveness of cholesterol - based liposomes in drug delivery.
2. **Cell Membrane Research**: A research team was studying the role of cholesterol in cell membrane fluidity. They added cholesterol at different concentrations to cell cultures and measured the membrane fluidity using fluorescence techniques. The results showed that the addition of cholesterol increased membrane rigidity at low concentrations and decreased it at high concentrations, providing valuable insights into the complex relationship between cholesterol and cell membrane properties.
If you have any questions or need further information about our Factory Supply Cholesterol Cas 57 - 88 - 5, please feel free to contact us. Our email address is info@vivalr.com, and our phone number is (86) 15866781826.
Este es William, CEO de Zhishang Chemical Co., Ltd.
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