1-Chlorobutane, with the CAS number 109-69-3, is an organic compound with the molecular formula C₄H₉Cl. It is a colorless, volatile liquid with a characteristic sweet odor. The boiling point of 1-chlorobutane is around 78 - 79 °C, and its melting point is -123.1 °C. It has a density of approximately 0.886 g/cm³ at 20 °C. This product is of high quality and is offered at a good price, making it an attractive option for various industrial and laboratory applications.
1-Chlorobutane has a wide range of uses in different industries. In the pharmaceutical industry, it serves as an important intermediate in the synthesis of various drugs. It can be used to introduce the butyl group into molecules, which is crucial for the biological activity of many pharmaceutical compounds. In the chemical industry, it is used in the production of other organic chemicals, such as butyl mercaptans, butyl amines, and butyl ethers. These chemicals are further used in the manufacturing of rubber, plastics, and pesticides.
In the laboratory, 1-chlorobutane is commonly used as a solvent for a variety of organic reactions. Its relatively low boiling point makes it easy to remove after the reaction is complete, which is beneficial for purification processes.
When using 1-chlorobutane, appropriate safety precautions should be taken. It should be handled in a well - ventilated area, preferably under a fume hood, as it is volatile and can release harmful vapors. Wear appropriate personal protective equipment, including safety goggles, gloves, and a lab coat.
For industrial applications, the product should be stored in a cool, dry place away from sources of ignition. When using it as a raw material in chemical reactions, follow the specific reaction procedures and conditions. For example, in a substitution reaction, it should be added gradually to the reaction mixture under controlled temperature and stirring conditions.
In the laboratory, when using it as a solvent, measure the required amount accurately using a pipette or a burette. After the reaction, the solvent can be removed by distillation or evaporation under reduced pressure.
Caso 1: Síntesis farmacéutica
A pharmaceutical company was synthesizing a new anti - inflammatory drug. They used 1 - chlorobutane as an intermediate to introduce the butyl group into the target molecule. By reacting 1 - chlorobutane with a specific nucleophile under carefully controlled reaction conditions, they were able to obtain the desired intermediate with a high yield. This intermediate was then further processed to produce the final drug product. The use of high - quality 1 - chlorobutane at a reasonable price helped the company reduce production costs while maintaining product quality.
Case 2: Chemical Manufacturing
A chemical plant was producing butyl mercaptan, which is used in the rubber industry. They used 1 - chlorobutane as the starting material. By reacting 1 - chlorobutane with sodium hydrosulfide in an appropriate solvent, they were able to synthesize butyl mercaptan efficiently. The proper handling and use of 1 - chlorobutane in the reaction process ensured a high conversion rate and a pure product output.
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