Factory Supply 5-Hydroxyoctanoic Acid Lactone (CAS 698-76-0) - High Purity & Competitive Price
Table of Contents
1. Product Overview
5-Hydroxyoctanoic Acid Lactone (CAS 698-76-0) is a high-purity organic compound widely used in pharmaceutical and chemical research. Key specifications include:
- Chemical Formula: C8H14O3
- Molecular Weight: 158.2 g/mol
- Appearance: White to off-white crystalline powder
- Purity: ≥98% (HPLC)
- Storage: 2-8°C in a dry, airtight container
2. Applications of 5-Hydroxyoctanoic Acid Lactone
This compound serves as a critical intermediate in:
- Pharmaceutical Synthesis: Used to produce chiral building blocks for antibiotics and anti-inflammatory drugs.
- Flavor & Fragrance Industry: Acts as a precursor for musk-like odorants.
- Polymer Chemistry: Key monomer for biodegradable polyester production.
- Biochemical Research: Studied for enzyme inhibition and metabolic pathways.
3. Usage Guidelines
Handling & Safety
- Wear PPE (gloves, goggles, lab coat) during handling.
- Use in a well-ventilated area or fume hood.
Recommended Procedures
- Solubility: Dissolve in dichloromethane or THF (10-20 mg/mL).
- Reaction Conditions: Typical use at 0.1-1.0 mol% in inert atmospheres.
- Purification: Column chromatography (silica gel, hexane/ethyl acetate).
4. Detailed Use Cases
Case 1: Synthesis of Biodegradable Polyesters
Process: 5-Hydroxyoctanoic Acid Lactone (5.0 g) was polymerized with ε-caprolactone (10:1 ratio) using Sn(Oct)2 as a catalyst at 120°C for 24 hours under nitrogen.
Result: Achieved 85% yield of a copolymer with Mn = 25,000 g/mol, suitable for medical implant coatings.
Case 2: Pharmaceutical Intermediate Preparation
Process: The lactone (2.0 mmol) underwent ring-opening with benzylamine in THF at 0°C, followed by NaBH4 reduction.
Result: Produced (R)-5-hydroxyoctanoamide (92% ee), a key intermediate in NSAID development.
5. Contact Information
For technical inquiries or bulk orders:
- Email: info@vivalr.com
- Phone: (86) 158 6678 1826