The product, Factory Supply 2,6 - di - O - methyl - beta - cyclOdextrin with CAS number 51166 - 71 - 3, is offered at a low price. Cyclodextrins are cyclic oligosaccharides composed of glucose units linked by α - 1,4 - glycosidic bonds. In the case of 2,6 - di - O - methyl - beta - cyclodextrin, it is a chemically modified form of beta - cyclodextrin.
Its molecular formula is C56H98O35, and it has a specific molecular weight. This product has good solubility in water and other polar solvents, which is beneficial for many applications. It exists as a white to off - white powder at room temperature, with high purity and stability.
1. Pharmaceutical Industry: It can be used as a drug carrier. The unique molecular structure of 2,6 - di - O - methyl - beta - cyclodextrin can form inclusion complexes with various drugs, improving the solubility, stability, and bioavailability of drugs. For example, it can enhance the dissolution rate of poorly soluble drugs, which is crucial for oral and injectable drug formulations.
2. Food Industry: In food products, it can be used as a flavor and fragrance encapsulant. It can effectively protect flavors and fragrances from environmental factors such as oxidation and evaporation, and control their release during food storage and consumption. It can also be used to remove unwanted substances in food, improving the quality and shelf - life of food products.
3. Cosmetics Industry: Due to its ability to form inclusion complexes, it can be used to improve the stability and efficacy of cosmetic ingredients. For example, it can enhance the solubility of oil - soluble vitamins and antioxidants in aqueous cosmetic formulations, making them more accessible to the skin.
1. Preparation of Inclusion Complexes: First, dissolve an appropriate amount of 2,6 - di - O - methyl - beta - cyclodextrin in water or a suitable solvent at a certain temperature, usually around 40 - 60°C. Then, add the guest molecule (such as a drug, flavor, or cosmetic ingredient) slowly under stirring. The molar ratio of the cyclodextrin to the guest molecule needs to be optimized according to the specific requirements. After adding, continue to stir for a certain period to ensure the formation of inclusion complexes.
2. Dosage: The dosage of 2,6 - di - O - methyl - beta - cyclodextrin depends on the application. In the pharmaceutical industry, the dosage may range from a few milligrams to several grams per dose, depending on the type of drug and the formulation. In the food and cosmetics industries, it is usually used in relatively small amounts, typically a few percent of the total formulation weight.
1. Pharmaceutical Case: A research team was working on a new anti - inflammatory drug with poor solubility. By using 2,6 - di - O - methyl - beta - cyclodextrin to form an inclusion complex with the drug, they found that the solubility of the drug increased by more than 10 times. In animal experiments, the bioavailability of the drug also improved significantly, which led to better therapeutic effects. The drug formulation was then successfully developed into an oral tablet for further clinical trials.
2. Food Case: A food company was trying to improve the stability of a natural fruit flavor in a beverage product. They added 2,6 - di - O - methyl - beta - cyclodextrin to the beverage formulation. After several months of storage at different temperatures, the flavor in the product with cyclodextrin retained more than 80% of its original intensity, while the control group without cyclodextrin lost more than half of its flavor. This shows that the cyclodextrin effectively protected the flavor from degradation.
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