2-Acetylthiophene, with the CAS number 88-15-3, is a crucial chemical compound. It appears as a colorless to light - yellow liquid or solid. The molecular formula of 2 - Acetylthiophene is C₆H₆OS, and its molecular weight is approximately 126.18 g/mol. The boiling point of this compound is around 213 - 214 °C, and it has a melting point of about 10 - 11 °C. It has a characteristic odor and is insoluble in water but soluble in common organic solvents such as ethanol, ether, and benzene. This product is often provided by factories in high - purity grades, ensuring its quality for various applications.
2 - Acetylthiophene has a wide range of uses in different industries. In the pharmaceutical field, it serves as an important intermediate for the synthesis of various drugs. Its unique chemical structure allows it to participate in numerous chemical reactions, which can be used to build complex drug molecules. For example, it can be used in the synthesis of anti - inflammatory and anti - cancer drugs.
In the fragrance industry, 2 - Acetylthiophene is used to create special scents. Its odor - related properties can add a unique and pleasant note to perfumes, colognes, and other fragrance products. It can also be used in the flavor industry to enhance the taste of food and beverage products, providing a special flavor profile.
In the field of materials science, it can be used as a monomer or additive in the synthesis of polymers. By incorporating 2 - Acetylthiophene into polymer structures, the physical and chemical properties of the polymers, such as solubility, thermal stability, and mechanical strength, can be improved.
When using 2 - Acetylthiophene, it is necessary to follow strict safety procedures. First, ensure that you are working in a well - ventilated area to avoid inhalation of fumes. Wear appropriate personal protective equipment, including safety glasses, gloves, and a lab coat.
In a laboratory setting, for chemical synthesis reactions, accurately measure the required amount of 2 - Acetylthiophene using appropriate measuring equipment, such as pipettes or weighing scales. Add it gradually to the reaction mixture under appropriate reaction conditions, such as temperature, pressure, and pH. Stir the reaction mixture thoroughly to ensure uniform distribution of the compound and efficient reaction.
In industrial applications, the storage and handling of 2 - Acetylthiophene should be carried out in accordance with relevant safety regulations. Store it in a cool, dry place away from heat sources and oxidizing agents. During transportation, use appropriate packaging materials to prevent leakage and damage.
Case 1: Pharmaceutical Synthesis
A pharmaceutical company was developing a new anti - inflammatory drug. They used 2 - Acetylthiophene as an intermediate in the synthesis process. By reacting 2 - Acetylthiophene with specific reagents under controlled conditions, they were able to synthesize a key intermediate compound. After several subsequent reaction steps, they successfully obtained the target anti - inflammatory drug. The use of high - purity 2 - Acetylthiophene from the factory supply ensured the high yield and quality of the final drug product.
Case 2: Fragrance Creation
A fragrance company aimed to create a new perfume with a unique and long - lasting scent. They added a small amount of 2 - Acetylthiophene to the perfume formula. The compound contributed a special, warm, and slightly sweet note to the perfume. After market testing, the new perfume received positive feedback from consumers, and sales increased significantly.
Case 3: Polymer Modification
A materials research group was working on improving the solubility of a certain polymer. They incorporated 2 - Acetylthiophene into the polymer structure through a copolymerization reaction. As a result, the solubility of the modified polymer in common organic solvents was greatly improved, which expanded its application range in coating and adhesive industries.
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