High Quality N4-Benzoylcytidine CAS 13089-48-0: Product Guide
Table of Contents
Introduction
N4-Benzoylcytidine (CAS 13089-48-0) is a chemically modified cytidine derivative widely used in oligonucleotide synthesis and pharmaceutical research. This guide provides detailed information about its specifications, applications, and best practices for handling.
Product Specifications
- CAS Number: 13089-48-0
- Molecular Formula: C16H17N3O6
- Molecular Weight: 347.33 g/mol
- Appearance: White to off-white crystalline powder
- Purity: ≥98% (HPLC)
- Storage: Store at -20°C in a dry, dark environment
Applications
N4-Benzoylcytidine serves as a critical reagent in:
- Oligonucleotide Synthesis: Protects cytidine residues during solid-phase RNA/DNA synthesis.
- Pharmaceutical Research: Used in the development of nucleotide-based therapeutics and antiviral agents.
- Biochemical Studies: Facilitates research on RNA structure, function, and modification mechanisms.
Usage Guidelines
- Storage: Keep sealed in original packaging under recommended conditions to prevent degradation.
- Handling: Use personal protective equipment (gloves, goggles) to avoid direct contact.
- Solubility: Dissolve in anhydrous DMF or DMSO for synthetic applications (typical concentration: 0.1-0.5M).
- Reaction Conditions: Employ under inert atmosphere (argon/nitrogen) for optimal stability during coupling reactions.
Case Studies
Case 1: RNA Oligonucleotide Synthesis
Researchers at XYZ Biotech utilized N4-Benzoylcytidine to synthesize a 25-mer RNA strand for CRISPR studies. The protected cytidine groups showed 99% coupling efficiency and minimal side reactions under standard phosphoramidite chemistry conditions.
Case 2: Antiviral Drug Development
In a recent study published in Journal of Medicinal Chemistry, N4-Benzoylcytidine was incorporated into a nucleotide prodrug targeting viral polymerases, demonstrating enhanced metabolic stability compared to unprotected cytidine analogs.
Contact Information
For technical inquiries or bulk orders:
- Email: info@vivalr.com
- Phone: (86) 15866781826



























