Chemical Name: Carbonic Acid, Methyl 2,2,2-Trifluoroethyl Ester
CAS Number: 156783-95-8
Molecular Formula: C4H5F3O3
Molecular Weight: 158.08 g/mol
Appearance: Clear, colorless liquid
Purity: ≥99% (GC analysis)
Packaging: Available in 1kg, 5kg, 25kg drums, or custom bulk orders.
Widely used as a fluorinated intermediate in organic synthesis, particularly for introducing trifluoroethyl groups into target molecules.
Critical in the production of active pharmaceutical ingredients (APIs) requiring trifluoroethyl ether moieties for enhanced bioavailability.
Employed in the synthesis of advanced herbicides and pesticides with improved stability and efficacy.
Store in a cool, dry place (2-8°C) under inert gas (N2/Ar). Use corrosion-resistant containers (e.g., stainless steel or PTFE-lined).
Wear PPE (gloves, goggles, lab coat). Use in well-ventilated areas or fume hoods. Incompatible with strong oxidizers and bases.
Typical use: 0.5-2.0 molar equivalents in anhydrous solvents (THF, DCM) at -20°C to 40°C. Monitor via TLC or GC-MS.
Used in a 3-step synthesis of a neuraminidase inhibitor precursor, achieving 78% overall yield with >99.5% purity (FDA-approved process).
Key fluorinated building block in TFT-LCD manufacturing, enabling low-voltage operation and high thermal stability (patented application).
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