CAS Number: 2631-72-3
Chemical Formula: C₈H₅BrCl₂O
Molecular Weight: 272.94 g/mol
Appearance: White to off-white crystalline powder
Purity: ≥98% (HPLC)
Storage: Store in a cool, dry place at 2-8°C, protected from light and moisture.
2-Bromo-2′,4′-dichloroacetophenone is a key intermediate in organic synthesis, widely used in:
Researchers utilized 2-Bromo-2′,4′-dichloroacetophenone (5 mmol) in a Suzuki-Miyaura cross-coupling reaction with boronic acid derivatives. The reaction, conducted under argon at 80°C for 12 hours, yielded a novel triazole derivative with 92% efficiency, demonstrating potent antifungal activity against Candida species.
In a 2023 study, the compound served as a precursor for synthesizing chlorinated acetophenone-based fungicides. A two-step halogen exchange process at 60°C in ethanol produced a high-purity agrochemical intermediate (99.2% purity), effective against wheat rust pathogens at 50 ppm concentration.
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