CAS Number: 2364548-02-5
Chemical Formula: C₂₅H₁₇Br
Molecular Weight: 397.31 g/mol
Appearance: White to off-white crystalline powder
Purity: ≥98% (HPLC)
Storage: Store at 2-8°C in a dry, dark environment
Soluble in THF, DCM, and DMF; insoluble in water
Typical use: 0.5-2 mol% in coupling reactions at 60-100°C under inert atmosphere
Used as a key intermediate in a Suzuki-Miyaura cross-coupling reaction to create blue-emitting materials. Achieved 92% yield under nitrogen at 80°C.
Employed in a Buchwald-Hartwig amination to develop kinase inhibitors, demonstrating excellent electron-withdrawing properties for bioactivity enhancement.
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