N-Methylmethanesulfonamide (CAS 1184-85-6) is a high-purity sulfonamide derivative widely used in industrial and research applications. Key specifications include:
N-Methylmethanesulfonamide serves critical roles in:
Process: Used as a sulfonating agent in the production of antiretroviral drugs. Reacted with aryl chlorides at 80°C under nitrogen, achieving 92% yield.
Example: Accelerated Suzuki-Miyaura coupling by 40% when used as a co-solvent with DMF, reducing reaction time to 3 hours.
Result: Added 2% w/w to polyamide resins, increasing heat resistance from 150°C to 190°C.
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