The product is Factory Supply 6-Hydroxypurine with the CAS number 68 - 94 - 0. 6 - Hydroxypurine, also known as Hypoxanthine, is an organic compound with the chemical formula C₅H₄N₄O. It belongs to the class of purine bases, which are fundamental components in nucleic acids (DNA and RNA).
Physically, it appears as a white to off - white crystalline powder. In terms of solubility, it has low solubility in water but can dissolve in alkaline solutions. Its melting point is around 285 - 290°C (dec.). The molecular weight of 6 - Hydroxypurine is approximately 136.11 g/mol.
6 - Hydroxypurine has several important uses in different fields. In the pharmaceutical industry, it serves as a key intermediate in the synthesis of various drugs. For example, it can be used in the development of antiviral and anticancer medications. Its purine structure is crucial for the design and production of drugs that target specific biological pathways related to DNA and RNA metabolism.
In the field of biochemistry and molecular biology, 6 - Hydroxypurine is used as a research tool. Scientists use it to study the structure and function of nucleic acids, as well as the enzymatic reactions involved in purine metabolism. It can also be used in cell culture media to support the growth of certain cell lines that have specific purine requirements.
In the food industry, it may be used in the production of flavor enhancers. Some purine - related compounds can contribute to the umami taste, and 6 - Hydroxypurine may be involved in such flavor - enhancing applications.
When using 6 - Hydroxypurine in a laboratory setting, it is important to follow strict safety protocols. Wear appropriate personal protective equipment, such as gloves and goggles, to avoid direct contact with the powder.
For dissolution, if using an alkaline solution, prepare the appropriate alkali (e.g., sodium hydroxide solution) at a suitable concentration. Slowly add the 6 - Hydroxypurine powder to the solution while stirring gently to ensure complete dissolution. The concentration of the solution should be adjusted according to the specific experimental requirements.
In drug synthesis, follow the established synthetic routes and reaction conditions. The reaction usually requires specific catalysts, solvents, and reaction temperatures. Carefully monitor the reaction progress using appropriate analytical techniques, such as thin - layer chromatography (TLC) or high - performance liquid chromatography (HPLC).
Case 1: Antiviral Drug Synthesis
A pharmaceutical research team was working on developing a new antiviral drug. They used 6 - Hydroxypurine as a starting material. The first step was to modify the purine ring structure by introducing specific functional groups. They dissolved 6 - Hydroxypurine in a mixture of organic solvents and reacted it with a halogenating agent under controlled temperature and pH conditions. After several purification steps using column chromatography, they obtained an intermediate compound with high purity. This intermediate was further reacted with other reagents to form the final antiviral drug candidate. In in vitro antiviral assays, the drug candidate showed significant inhibitory effects against a particular virus strain.
Case 2: Cell Culture
A cell biology laboratory was culturing a specific type of mammalian cells that had a high demand for purines. They added 6 - Hydroxypurine to the cell culture media at a concentration of 10 μM. The cells showed improved growth and viability compared to the control group without 6 - Hydroxypurine. After several passages, the cells maintained their normal morphological and functional characteristics, indicating that 6 - Hydroxypurine effectively supported the cell growth requirements.
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