The product we are introducing here is Factory Supply 4-Bromoindole with the CAS number 52488-36-5. It is offered at a low price, which makes it an attractive option for various industries. The molecular formula of 4-Bromoindole is C8H6BrN, and its molecular weight is approximately 196.04 g/mol. It appears as a light yellow to brown crystalline powder. The melting point of this product is typically in the range of 57 - 61°C. It is insoluble in water but soluble in common organic solvents such as ethanol, ether, and chloroform. The high - purity grade of 4 - Bromoindole ensures reliable performance in its applications.
4 - Bromoindole is a crucial intermediate in organic synthesis. In the pharmaceutical industry, it is widely used in the synthesis of various drugs. It can serve as a building block for the development of drugs with anti - cancer, anti - inflammatory, and anti - microbial properties. For instance, researchers can modify the 4 - Bromoindole structure to design new drugs that target specific disease - related proteins. In the field of agrochemicals, it is used to synthesize pesticides and herbicides. The unique chemical structure of 4 - Bromoindole allows it to introduce specific functional groups into the molecular structure of agrochemicals, enhancing their efficacy and selectivity. Moreover, it is also used in the production of dyes and pigments. The bromine atom in 4 - Bromoindole can participate in chemical reactions to form stable chromophores, which can be used to develop new types of dyes with excellent color fastness and light resistance.
When using 4 - Bromoindole, proper safety precautions should be taken. It is recommended to wear appropriate protective equipment, such as gloves, goggles, and a lab coat. In the laboratory or industrial settings, it should be stored in a cool, dry place away from direct sunlight and sources of ignition. When handling this product, it should be done in a well - ventilated area to avoid inhalation of dust. In a chemical reaction, 4 - Bromoindole should be added gradually to the reaction mixture under stirring to ensure uniform reaction. The reaction conditions, such as temperature, pressure, and reaction time, should be carefully controlled according to the specific reaction requirements. After the reaction, proper purification steps should be carried out to obtain the desired product with high purity.
Pharmaceutical Synthesis Example: In a research project aiming to develop a new anti - cancer drug, 4 - Bromoindole was used as a starting material. First, it was reacted with a specific amine compound in the presence of a palladium catalyst under an inert atmosphere. The reaction was carried out at 80°C for 6 hours. After the reaction, the crude product was purified by column chromatography, and a key intermediate was obtained. This intermediate was further modified through several chemical reactions, including acylation and alkylation, to finally obtain the target anti - cancer drug. In vitro and in vivo tests showed that the new drug had significant inhibitory effects on cancer cell growth.
Agrochemical Synthesis Example: In the synthesis of a new herbicide, 4 - Bromoindole was reacted with a chloro - substituted aromatic compound in the presence of a base. The reaction was carried out in an organic solvent at room temperature for 12 hours. After work - up and purification, the resulting product was formulated into a herbicide. Field tests showed that this herbicide had excellent weed control efficacy and low toxicity to crops.
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This is William, CEO of Zhishang Chemical Co., Ltd.
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